Abstract: X-ray angiography provides two-dimensional projections of opacified arteries. Utilizing temporally synchronized projections, from different angles, a 3D model can be reconstructed. Biplane angiography [1] systems can provide two simultaneous acquisitions, but are not as widely available as single-view systems. Using the latter systems, the different projections are acquired sequentially. During the time required to change the position of the imaging system, patient motion or breathing motion may be introduced. We propose a method to construct a 3D+t model of the coronary tree from non-simultaneous sequences, synchronized with the electrocardiogram and acquired on single-view angiography systems.