Global Analysis of New Malaria Intrahost Models with a Competitive Exclusion Principle - Inria - Institut national de recherche en sciences et technologies du numérique Accéder directement au contenu
Article Dans Une Revue SIAM Journal on Applied Mathematics Année : 2006

Global Analysis of New Malaria Intrahost Models with a Competitive Exclusion Principle

Résumé

In this paper we propose a malaria within-host model with k classes of age for the parasitized red blood cells and n strains for the parasite. We provide a global analysis for this model. A competitive exclusion principle holds. If R0, the basic reproduction number, satisfies R0 ≤ 1, then the disease-free equilibrium is globally asymptotically stable. On the contrary if R0 > 1, then generically there is a unique endemic equilibrium which corresponds to the endemic stabilization of the most virulent parasite strain and to the extinction of all the other parasites strains. We prove that this equilibrium is globally asymptotically stable on the positive orthant if a mild sufficient condition is satisfied.
Fichier principal
Vignette du fichier
64327c.pdf (259.47 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

inria-00552014 , version 1 (05-01-2011)

Identifiants

Citer

Abderrahman Iggidr, Jean-Claude Kamgang, Gauthier Sallet, Jean-Jules Tewa. Global Analysis of New Malaria Intrahost Models with a Competitive Exclusion Principle. SIAM Journal on Applied Mathematics, 2006, 67 (1), pp.260-278. ⟨10.1137/050643271⟩. ⟨inria-00552014⟩
200 Consultations
348 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More