The genetical bandwidth mapping: a spatial and graphical representation of population genetic structure based on the Wombling method.

A. Cercueil; O. François; S. Manel

hal-00370259, version 1

The genetical bandwidth mapping: a spatial and graphical representation of population genetic structure based on the Wombling method.

A. Cercueil ¹, O. François ^1, 2, 3, S. Manel ⁴

Theoretical Population Biology 71, 3 (2007) 332-41

Abstract: Characterizing the spatial variation of allele frequencies in a population has a wide range of applications in population genetics. This article introduces a new nonparametric method, which provides a two-dimensional representation of a structural parameter called the genetical bandwidth, which describes genetic structure around arbitrary spatial locations in a study area. This parameter corresponds to the shortest distance to areas of significant allele variation, and its computation is based on the Womble's systemic function. A simulation study and application to data sets taken from the literature give evidence that the method is particularly demonstrative when the fine-scale structure is stronger than the large-scale structure, and that it is generally able to locate genetic boundaries or clines precisely.

1: Techniques de l'Ingénierie Médicale et de la Complexité (TIMC)
CNRS : UMR5525 – Université Joseph Fourier - Grenoble I
2: Laboratoire de Modélisation et Calcul (LMC - IMAG)
CNRS : UMR5523 – Université Joseph Fourier - Grenoble I – Institut National Polytechnique de Grenoble (INPG)
3: MISTIS (INRIA Grenoble Rhône-Alpes / LJK Laboratoire Jean Kuntzmann)
INRIA – Laboratoire Jean Kuntzmann
4: Laboratoire d'écologie alpine (LECA)
CNRS : UMR5553 – Université Joseph Fourier - Grenoble I – Université de Savoie

hal-00370259, version 1
http://hal.archives-ouvertes.fr/hal-00370259
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From: Olivier Francois <>
Submitted on: Tuesday, 24 March 2009 08:49:42
Updated on: Wednesday, 25 March 2009 12:16:38

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PubMed: 17353024

DOI: 10.1016/j.tpb.2007.01.007

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