''Classical'' Electropermeabilization Modeling at the Cell Scale

Otared Kavian; Michael Leguèbe; Clair Poignard; Lisl Weynans

hal-00712683, version 2

''Classical'' Electropermeabilization Modeling at the Cell Scale

Otared Kavian ¹, Michael Leguèbe () ^2, 3, Clair Poignard ( Author to contact preferably )^a^, 2, 3, Lisl Weynans () ^2, 3

N° RR-8005 (2012)

Abstract: In this paper we derive two models (a static and a dynamical model) based on the description of the electric potential in a biological cell in order to model the cell electropermeabili-zation. Existence and uniqueness results for each model are provided, and accurate numerical method to compute the solution is presented. We then present numerical results that corroborate the experimental results, justifying the validity of our modeling. We emphasize that our new models involve very few parameters, compared with the most achieved model but they describe the same qualitative results. Moreover our numerical resultsare quantitavely close to the experimental data.

a – INRIA
1: Laboratoire de Mathématiques de Versailles (LM-Versailles)
CNRS : UMR8100 – Université de Versailles Saint-Quentin-en-Yvelines
2: MC2 (INRIA Bordeaux - Sud-Ouest)
INRIA – Université Sciences et Technologies - Bordeaux I – Université Victor Segalen - Bordeaux II – CNRS : UMR
3: Institut de Mathématiques de Bordeaux (IMB)
CNRS : UMR5251 – Université Sciences et Technologies - Bordeaux I – Université Victor Segalen - Bordeaux II

hal-00712683, version 2
http://hal.inria.fr/hal-00712683
oai:hal.inria.fr:hal-00712683
From: Clair Poignard <>
Submitted on: Monday, 9 July 2012 20:14:55
Updated on: Tuesday, 10 July 2012 08:34:46

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