inria-00000242, version 1

Refined localization of twenty-one genes in subregion p13.1 of human chromosome 1

Claude Chelala ¹, Sandrine Imbeaud ¹, Marie-Dominique Devignes () ², Rima Zoorob ¹, Charles Auffray ¹

Cytogenetics and Cell Genetics 92, 3-4 (2001) 209-212

• 1:  Genexpress
• 
  CNRS : ERS1984 19 rue Guy Môquet, BP8, F-94801 Villejuif Cedex France
• 2:  LANGUE ET DIALOGUE (INRIA Lorraine - LORIA)
• 
  INRIA – CNRS : UMR7503 – Université Henri Poincaré - Nancy I – Université Nancy II – Institut National Polytechnique de Lorraine (INPL) France

Bibliographic reference

• Type of document: Articles in peer-reviewed journal
• Domain: Life Sciences/Biochemistry, Molecular Biology/Genomics
• Title: Refined localization of twenty-one genes in subregion p13.1 of human chromosome 1
• Abstract: In this report, we describe a refinement of the human transcript map of chromosome 1p13.1, a subregion undergoing many aberrations in various types of human cancers. Publicly available genetic linkage, radiation hybrid and physical maps, as well as cytogenetic and sequence data were used to establish the relative order and orientation of ten known intragenic markers. The complete sequence of genomic clones of the region, available at the Sanger Centre, provided the tool for further studies performed by BLAST analysis against all cDNA sequences registered in the Genexpress Index2. This allowed us to assign to subband 1p13.1 nine of the ten known genes, an additional member of the gene family of one of these genes and eleven new transcripts. The remaining known gene and one additional new transcript map at the 1p13.1 and 1p13.2 boundary. The corresponding genes may be responsible for disorders related to this region. The resulting transcript map of 1p13.1 is presented in the printed article with additional data available on a dedicated Web site at the address http://idefix.upr420.vjf.cnrs.fr/CARTO
• Full text language: English
• Journal title:

  Cytogenetics and Cell Genetics
  Publisher	S Karger AG
  ISSN	0301-0171 (eISSN : 1421-9816)

• Publication date: 2001
• Audience: not specified
• Commercial editor: Karger
• Volume: 92
• Number: 3-4
• Pagination: 209-212
• DOI: 10.1159/000056904
• Comment: http://content.karger.com

• inria-00000242, version 1
• http://hal.inria.fr/inria-00000242
• oai:hal.inria.fr:inria-00000242
• From: Marie-Dominique Devignes <>
• Submitted on: Friday, 16 September 2005 12:37:36
• Updated on: Thursday, 6 October 2005 16:16:18