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Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

Cyril Planchais , Remi Noe , Marie Gilbert , Maxime Lecerf , Srini V Kaveri , et al.
Communications Biology, 2023, 6, pp.168. ⟨10.1038/s42003-023-04535-5⟩
Article dans une revue hal-03988037v1
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Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

Valerie Lorin , Ignacio Fernández , Guillemette Masse-Ranson , Mélanie Bouvin-Pley , Luis M. Molinos-Albert , et al.
Journal of Experimental Medicine, 2022, 219 (3), pp.e20212045. ⟨10.1084/jem.20212045⟩
Article dans une revue pasteur-03654254v1
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Tocilizumab-treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants

Camille Chauvin , Laurine Levillayer , Mathilde Roumier , Hubert Nielly , Claude Roth , et al.
iScience, 2023, 26 (3), pp.106124. ⟨10.1016/j.isci.2023.106124⟩
Article dans une revue hal-04090334v1
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Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis

Marie Armani-Tourret , Zhicheng Zhou , Romain Gasser , Isabelle Staropoli , Vincent Cantaloube-Ferrieu , et al.
PLoS Pathogens, 2021, 17 (4), pp.e1009526. ⟨10.1371/journal.ppat.1009526⟩
Article dans une revue hal-03204143v1
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Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells

Jérémy Dufloo , Cyril Planchais , Stéphane Frémont , Valerie Lorin , Florence Guivel-Benhassine , et al.
Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Article dans une revue pasteur-03654220v1
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TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice

Véronique Godot , Colas Tcherakian , Laurine Gil , Iñaki Cervera-Marzal , Guangming Li , et al.
PLoS Pathogens, 2020, 16, ⟨10.1371/journal.ppat.1009025⟩
Article dans une revue hal-04296375v1
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Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers

Luis Molinos-Albert , Valerie Lorin , Valérie Monceaux , Sylvie Orr , Asma Essat , et al.
Nature Communications, 2022, 13 (1), pp.1944. ⟨10.1038/s41467-022-29511-1⟩
Article dans une revue pasteur-03654232v1
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Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

Valérie Lorin , Anne Danckaert , Françoise Porrot , Olivier Schwartz , Philippe Afonso , et al.
mBio, 2020, 11 (5), pp.e02424-20. ⟨10.1128/mBio.02424-20⟩
Article dans une revue pasteur-03246667v1
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Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Delphine Planas , Isabelle Staropoli , Vincent Michel , Frederic Lemoine , Flora Donati , et al.
Nature Communications, 2024, 15 (1), pp.2254. ⟨10.1038/s41467-024-46490-7⟩
Article dans une revue pasteur-04530809v1
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Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

Nikaïa Smith , Pedro Goncalves , Bruno Charbit , Ludivine Grzelak , Maxime Beretta , et al.
Nature Immunology, 2021, ⟨10.1038/s41590-021-01028-7⟩
Article dans une revue pasteur-03384279v1
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Identification, caractérisation moléculaire et étude des propriétés fonctionnelles des anticorps neutralisants à large spectre contre le VIH-1

Valérie Lorin
Sciences agricoles. Université Paris Cité, 2020. Français. ⟨NNT : 2020UNIP7199⟩
Thèse tel-03339927v1

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller

Luis M Molinos-Albert , Eduard Baquero , Mélanie Bouvin-Pley , Valerie Lorin , Caroline Charre , et al.
Cell Host & Microbe, 2023, 31 (8), pp.1275-1287.e8. ⟨10.1016/j.chom.2023.06.006⟩
Article dans une revue pasteur-04168501v1
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Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies

Timothée Bruel , Karl Stéfic , Yann Nguyen , Donatella Toniutti , Isabelle Staropoli , et al.
Cell Reports Medicine, 2022, 3 (12), pp.100850. ⟨10.1016/j.xcrm.2022.100850⟩
Article dans une revue pasteur-04165260v1
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Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

Jonathan Torres , Gabriel Ozorowski , Emanuele Andreano , Hejun Liu , Jeffrey Copps , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (20), pp.e2120976119. ⟨10.1073/pnas.2120976119⟩
Article dans une revue pasteur-04082754v1
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High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1

William Bolland , Vincent Michel , Delphine Planas , Mathieu Hubert , Isabelle Staropoli , et al.
Journal of Virology, In press, pp.e0135123. ⟨10.1128/jvi.01351-23⟩
Article dans une revue pasteur-04369613v1
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A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

Ludivine Grzelak , Sarah Temmam , Cyril Planchais , Caroline Demeret , Laura Tondeur , et al.
Science Translational Medicine, 2020, 12 (559), pp.eabc3103. ⟨10.1126/scitranslmed.abc3103⟩
Article dans une revue pasteur-03139185v1
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A monocyte/dendritic cell molecular signature of SARS-CoV2-related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis

Camille de Cevins , Marine Luka , Nikaïa Smith , Sonia Meynier , Aude Magérus , et al.
2021
Pré-publication, Document de travail pasteur-03244400v1

The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 Variants

Stacy Gellenoncourt , Nell Saunders , Rémy Robinot , Lucas Auguste , Maaran Michael Rajah , et al.
Journal of Virology, 2022, 96 (19), pp.e0130122. ⟨10.1128/jvi.01301-22⟩
Article dans une revue pasteur-04082631v1
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Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies

Delphine Planas , Timothée Bruel , Isabelle Staropoli , Florence Guivel-Benhassine , Françoise Porrot , et al.
Nature Communications, 2023, 14 (1), pp.824. ⟨10.1038/s41467-023-36561-6⟩
Article dans une revue hal-04087563v1

Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies

Delphine Planas , Timothée Bruel , Isabelle Staropoli , Florence Guivel-Benhassine , Françoise Porrot , et al.
bioRxiv : the preprint server for biology, 2022, ⟨10.1101/2022.11.17.516888⟩
Article dans une revue pasteur-04082579v1
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TMPRSS2 is a functional receptor for human coronavirus HKU1

Nell Saunders , Ignacio Fernandez , Cyril Planchais , Vincent Michel , Maaran Michael Rajah , et al.
Nature, 2023, 624 (7990), pp.207-214. ⟨10.1038/s41586-023-06761-7⟩
Article dans une revue hal-04372694v1
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Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission

Xiaoyu Luo , Hugo Mouquet , Olivier Schwartz , Warner C. Greene
Journal of Biological Chemistry, 2021, 297 (4), pp.101098. ⟨10.1016/j.jbc.2021.101098⟩
Article dans une revue pasteur-03696818v1
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Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2

Cyril Planchais , Alejandra Reyes-Ruiz , Robin Lacombe , Alessandra Zarantonello , Maxime Lecerf , et al.
Protein Science, 2022, 31 (11), pp.e4447. ⟨10.1002/pro.4447⟩
Article dans une revue hal-03835297v1
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An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa

Benjamin Vesin , Jodie Lopez , Amandine Noirat , Pierre Authié , Ingrid Fert , et al.
Molecular Therapy, 2022, ⟨10.1016/j.ymthe.2022.04.016⟩
Article dans une revue pasteur-03695076v1
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Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3

Karunasinee Suphaphiphat , Monica Tolazzi , Stéphane Hua , Delphine Desjardins , Valerie Lorin , et al.
EBioMedicine, 2020, 57, pp.102842. ⟨10.1016/j.ebiom.2020.102842⟩
Article dans une revue hal-03491095v1
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Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas

Hannah Barbian , Julie Decker , Frederic Bibollet-Ruche , Rachel Galimidi , Anthony West , et al.
mBio, 2015, 6 (2), ⟨10.1128/mBio.00296-15⟩
Article dans une revue cea-02530869v1

Syncytia formation by SARS‐CoV‐2‐infected cells

Julian Buchrieser , Jérémy Dufloo , Mathieu Hubert , Blandine Monel , Delphine Planas , et al.
EMBO Journal, 2020, 39 (23), pp.e106267. ⟨10.15252/embj.2020106267⟩
Article dans une revue pasteur-03253133v1
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Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2

Cyril Planchais , Ignacio Fernández , Timothée Bruel , Guilherme Dias de Melo , Matthieu Prot , et al.
Journal of Experimental Medicine, 2022, 219 (7), pp.e20220638. ⟨10.1084/jem.20220638⟩
Article dans une revue hal-03697587v1
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HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria

Cyril Planchais , Luis M Molinos-Albert , Pierre Rosenbaum , Thierry Hieu , Alexia Kanyavuz , et al.
Nature Communications, 2023, 14 (1), pp.6326. ⟨10.1038/s41467-023-42027-6⟩
Article dans une revue hal-04248132v1
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CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues

Nicolas Huot , Philippe Rascle , Cyril Planchais , Vanessa Contreras , Caroline Passaes , et al.
Frontiers in Immunology, 2021, 12, pp.695148. ⟨10.3389/fimmu.2021.695148⟩
Article dans une revue pasteur-03278887v1