Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its Sequence -Structure -Function analysis

Abstract : Background. Non-specific Lipid Transfer Proteins (nsLTPs) are widely distributed in the plant kingdom and constitute a superfamily of related proteins. More than 800 different sequences have been characterized so far, but their biological functions remain unclear. It has been clear for years that they present a certain interest for agronomic and nutritional issues. Deciphering their functions means collecting and analyzing a variety of data from gene sequence to protein structure, from cellular localization to the physiological role. As a huge and growing number of new protein sequences are available nowadays, extracting meaningful knowledge from sequence-structure-function relationships calls for the development of new tools and approaches. As nsLTPs show high evolutionary divergence, but a conserved common right-handed superhelix structural fold, and as they are involved in a large number of key roles in plant development and defense, they are a stimulating case study for validating such an approach.
Complete list of metadatas

Cited literature [71 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-02112505
Contributor : Frédéric de Lamotte <>
Submitted on : Tuesday, October 1, 2019 - 6:04:16 PM
Last modification on : Thursday, October 10, 2019 - 5:05:08 PM

File

peerj-7504-2S.pdf
Publisher files allowed on an open archive

Identifiers

Collections

Citation

Cécile Fleury, Jérôme Gracy, Marie-Françoise Gautier, Jean-Luc Pons, Jean-François Dufayard, et al.. Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its Sequence -Structure -Function analysis. PeerJ, PeerJ, 2019, 7, pp.e7504. ⟨10.7287/peerj.preprints.27687v1⟩. ⟨hal-02112505⟩

Share

Metrics

Record views

31

Files downloads

75