P. Baumann, Biology of bacteriocyte-associated endosymbionts of plant sap-sucking insects, Annu Rev Microbiol, vol.59, pp.155-189, 2005.

L. M. Birkle, L. B. Minto, D. , and A. E. , Relating genotype and phenotype for tryptophan synthesis in an aphid-bacterial symbiosis, Physiol Entomol, vol.27, pp.1-17, 2002.
DOI : 10.1046/j.1365-3032.2002.00301.x

A. M. Bracho, D. Martínez-torres, A. Moya, and A. Latorre, Discovery and molecular characterization of a plasmid localized in Buchnera sp. bacterial endosymbiont of the aphid Rhopalosiphum padi, J Mol Evol, vol.41, pp.67-73, 1994.

L. Brinza, J. Viñuelas, L. Cottret, F. Calevro, Y. Rahbé et al., Systemic analysis of the symbiotic function of Buchnera aphidicola, the primary endosymbiont of the pea aphid Acyrthosiphon pisum, C R Biol, vol.332, pp.1034-1049, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00445861

L. Brinza, F. Calevro, G. Duport, K. Gaget, C. Gautier et al., Structure and dynamics of the operon map of Buchnera aphidicola sp, strain APS. BMC Genomics, vol.11, p.666, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00632959

F. Calevro, H. Charles, N. Reymond, V. Dugas, J. P. Cloarec et al., Assessment of 35mer amino-modified oligonucleotide based microarray with bacterial samples, J Microbiol Methods, vol.57, pp.207-218, 2004.
URL : https://hal.archives-ouvertes.fr/hal-00402180

D. E. Chang, D. J. Smalley, C. , and T. , Gene expression profiling of Escherichia coli growth transitions: an expanded stringent response model, Mol Microbiol, vol.45, pp.289-306, 2002.
DOI : 10.1046/j.1365-2958.2002.03001.x

URL : https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2958.2002.03001.x

S. Charaniya, S. Mehra, W. Lian, K. P. Jayapal, G. Karypis et al., Transcriptome dynamics-based operon prediction and verification in Streptomyces coelicolor, Nucleic Acids Res, vol.35, pp.7222-7236, 2007.
DOI : 10.1093/nar/gkm501

URL : https://academic.oup.com/nar/article-pdf/35/21/7222/16757981/gkm501.pdf

H. Charles and H. Ishikawa, Physical and genetical map of the genome of Buchnera, the primary endosymbiont of the pea aphid Acyrthosiphon pisum, J Mol Evol, vol.48, pp.142-150, 1999.

H. Charles, F. Calevro, J. Viñuelas, J. M. Fayard, R. et al., Codon usage bias and tRNA overexpression in Buchnera aphidicola after aromatic amino acid nutritional stress on its host Acyrthosiphon pisum, Nucleic Acids Res, vol.34, pp.4583-4592, 2006.
DOI : 10.1093/nar/gkl597

URL : https://hal.archives-ouvertes.fr/hal-00391277

G. De-la-cueva-méndez and B. Pimentel, Gene and cell survival: lessons from prokaryotic plasmid R1, EMBO Rep, vol.8, pp.458-464, 2007.

D. O. Daley, M. Rapp, E. Granseth, K. Melen, D. Drew et al., Global topology analysis of the Escherichia coli inner membrane proteome, Science, vol.308, pp.1321-1323, 2005.

A. E. Douglas, Sulphate utilization in an aphid symbiosis, Insect Biochem, vol.18, pp.599-605, 1988.
DOI : 10.1016/0020-1790(88)90012-1

A. E. Douglas and W. A. Prosser, Synthesis of the essential amino acid tryptophan in the pea aphid (Acyrthosiphon pisum) symbiosis, J Insect Physiol, vol.38, pp.565-568, 1992.

A. E. Douglas, L. B. Minto, and T. L. Wilkinson, Quantifying nutrient production by the microbial symbionts in an aphid, J Exp Biol, vol.204, pp.349-358, 2001.

T. Durfee, A. M. Hansen, H. Zhi, F. R. Blattner, J. et al., Transcription profiling of the stringent response in Escherichia coli, J Bacteriol, vol.190, pp.1084-1096, 2008.

G. Febvay, B. Delobel, R. , and Y. , Influence of the amino acid balance on the improvement of an artificial diet for a biotype of Acyrthosiphon pisum (Homoptera: Aphididae), Can J Zool, vol.66, pp.2449-2453, 1988.

G. Febvay, I. Liadouze, J. Guillaud, and G. Bonnot, Analysis of energetic aminoacid metabolism in Acyrthosiphon pisum: a multidimensional approach to amino acid metabolism in aphids, Arch Insect Biochem Physiol, vol.29, pp.45-69, 1995.

G. Febvay, Y. Rahbé, M. Rynkiewicz, J. Guillaud, and G. Bonnot, Fate of dietary sucrose and neosynthesis of amino acids in the pea aphid, Acyrthosiphon pisum, reared on different diets, J Exp Biol, vol.202, pp.2639-2652, 1999.
URL : https://hal.archives-ouvertes.fr/hal-00402190

S. Gattolin, H. J. Newbury, J. S. Bale, H. M. Tseng, D. A. Barrett et al., A diurnal component to the variation in sieve tube amino acid content in wheat, Plant Physiol, vol.147, pp.912-921, 2008.

M. Gholami, B. G. Coombe, R. , and S. R. , , p.1283, 2004.

, Grapevine phloem sap analysis: 1-sucrose, amino acids, potassium concentrations, seasonal and diurnal patterns, Acta Hort (ISHS), vol.640, pp.143-153

R. Gil, B. Sabater-muñoz, V. Pérez-brocal, F. J. Silva, and A. Latorre, Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest genomes. A puzzling evolutionary story, Gene, vol.370, pp.17-25, 2006.

R. C. Van-ham, A. Moya, and A. Latorre, Putative evolutionary origin of plasmids carrying the genes involved in leucine biosynthesis in Buchnera aphidicola (endosymbiont of aphids), J Bacteriol, vol.179, pp.4768-4777, 1997.

R. C. Van-ham, J. Kamerbeek, C. Palacios, C. Rausell, F. Abascal et al., Reductive genome evolution in Buchnera aphidicola, Proc Natl Acad Sci, vol.100, pp.581-586, 2003.

, Genome sequence of the pea aphid Acyrthosiphon pisum, International Aphid Genomics Consortium, vol.8, p.1000313, 2010.

A. B. Khodursky, B. J. Peter, N. R. Cozzarelli, D. Botstein, P. O. Brown et al., DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli, Proc Natl Acad Sci, vol.97, pp.12170-12175, 2000.

C. L. Kingsford, K. Ayanbule, and S. L. Salzberg, Rapid, accurate, computational discovery of Rhoindependent transcription terminators illuminates their relationship to DNA uptake, Genome Biol, vol.8, p.22, 2007.

A. Latorre, R. Gil, F. J. Silva, M. , and A. , Chromosomal stasis versus plasmid plasticity in aphid endosymbiont Buchnera aphidicola, Heredity, vol.95, pp.339-347, 2005.
DOI : 10.1038/sj.hdy.6800716

URL : https://www.nature.com/articles/6800716.pdf

I. Liadouze, G. Febvay, J. Guillaud, and G. Bonnot, Effect of diet on the free amino acid pools of symbiotic and aposymbiotic pea aphids, Acyrthosiphon pisum, J Insect Physiol, vol.41, pp.33-40, 1995.

R. Maas, J. Oppenheim, S. Saadi, T. Fuchs, and W. K. Maas, Isolation and properties of the RepA1 protein of the IncFII replicon, RepFIC. Mol Microbiol, vol.5, pp.927-932, 1991.

S. J. Macdonald, G. H. Thomas, D. , and A. E. , Genetic and metabolic determinants of nutritional phenotype in an insect-bacterial symbiosis, Mol Ecol, vol.20, pp.2073-2084, 2011.

N. A. Moran and P. H. Degnan, Functional genomics of Buchnera and the ecology of aphid hosts, Mol Ecol, vol.15, pp.1251-1261, 2006.

N. A. Moran, M. A. Munson, P. Baumann, and H. Ishikawa, A molecular clock in endosymbiotic bacteria is calibrated using the insect hosts, Proc R Soc B, vol.253, pp.167-171, 1993.

N. A. Moran, G. R. Plague, J. P. Sandstrom, and J. L. Wilcox, A genomic perspective on nutrient provisioning by bacterial symbionts of insects, Proc Natl Acad Sci, vol.100, pp.14543-14548, 2003.

N. A. Moran, H. E. Dunbar, and J. L. Wilcox, Regulation of transcription in a reduced bacterial genome: nutrient-provisioning genes of the obligate symbiont Buchnera aphidicola, J Bacteriol, vol.187, pp.4229-4237, 2005.

N. A. Moran, H. J. Mclaughlin, and R. Sorek, The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria, Science, vol.323, pp.379-382, 2009.

J. H. Park, K. H. Lee, T. Y. Kim, and S. Y. Lee, Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation, Proc Natl Acad Sci, vol.104, pp.7797-7802, 2007.

J. Pate, E. Shedley, D. Arthur, A. , and M. , Spatial and temporal variations in phloem sap composition of plantation-grown Eucalyptus globulus, Oecologia, vol.117, pp.312-322, 1998.

V. Pérez-brocal, R. Gil, S. Ramos, A. Lamelas, M. Postigo et al., A small microbial genome: the end of a long symbiotic relationship, Science, vol.314, pp.312-313, 2006.

M. W. Pfaffl, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res, vol.29, p.45, 2001.

M. W. Pfaffl, G. W. Horgan, D. , and L. , Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR, Nucleic Acids Res, vol.30, p.36, 2002.

M. W. Pfaffl, A. Tichopad, C. Prgomet, and T. P. Neuvians, Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper-Excel-based tool using pair-wise correlations, Biotechnol Lett, vol.26, pp.509-515, 2004.

G. R. Plague, C. Dale, and N. A. Moran, Low and homogeneous copy number of plasmid-borne symbiont genes affecting host nutrition in Buchnera aphidicola of the aphid Uroleucon ambrosiae, Mol Ecol, vol.12, pp.1095-1100, 2003.

Y. Rahbé and G. Febvay, Protein toxicity to aphidsan in vitro test on Acyrthosiphon pisum, Entomol Exp Appl, vol.67, pp.149-160, 1993.

Y. Rahbé, M. C. Digilio, G. Febvay, J. Guillaud, P. Fanti et al., Metabolic and symbiotic interactions in amino acid pools of the pea aphid Acyrthosiphon pisum parasitized by the braconid Aphidius ervi, J Insect Physiol, vol.48, pp.507-516, 2002.

N. Reymond, F. Calevro, J. Viñuelas, N. Morin, Y. Rahbé et al., Different levels of transcriptional regulation due to trophic constraints in the reduced genome of, Buchnera aphidicola APS. Appl Environ Microbiol, vol.72, pp.7760-7766, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00391509

W. Rychlik, OLIGO 7 primer analysis software, Methods Mol Biol, vol.402, pp.35-60, 2007.

B. Sabater-muñoz, R. C. Van-ham, A. Moya, F. J. Silva, and A. Latorre, Evolution of the leucine gene cluster in Buchnera aphidicola: insights from chromosomal versions of the cluster, J Bacteriol, vol.186, pp.2646-2654, 2004.

T. Sasaki and H. Ishikawa, Production of essential amino acids from glutamate by mycetocyte symbionts of the pea aphid, Acyrthosiphon pisum, J Insect Physiol, vol.41, pp.41-46, 1995.

N. Sauvion, H. Charles, G. Febvay, R. , and Y. , Effects of the jackbean lectin (ConA) on the feeding behaviour and kinetics of intoxication of the pea aphid, Acyrthosiphon pisum (Harris), Entomol Exp Appl, vol.10, pp.31-44, 2004.

P. J. Sharkey, P. , and J. S. , Translocation from leaves to fruits of a legume, studied by a phloem bleeding technique: diurnal changes and effects of continuous darkness, Planta, vol.128, pp.63-72, 1976.

S. Shigenobu, H. Watanabe, M. Hattori, Y. Sakaki, and H. Ishikawa, Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp, Nature, vol.407, pp.81-86, 2000.

F. J. Silva, R. C. Van-ham, B. Sabater, and A. Latorre, Structure and evolution of the leucine plasmids carried by the endosymbiont (Buchnera aphidicola) from aphids of the family Aphididae, FEMS Microbiol Lett, vol.168, pp.43-49, 1998.

J. A. Smith and J. A. Miburn, Phloem transport, solute flux and the kinetics of sap exudation in Ricinus communis L, Planta, vol.148, pp.35-41, 1980.

T. Soler, A. Latorre, B. Sabater, and F. J. Silva, Molecular characterization of the leucine plasmid from Buchnera aphidicola, primary endosymbiont of the aphid Acyrthosiphon pisum, Curr Microbiol, vol.40, pp.264-268, 2000.

B. E. Suzek, M. D. Ermolaeva, M. Schreiber, and S. L. Salzberg, A probabilistic method for identifying start codons in bacterial genomes, Bioinformatics, vol.17, pp.1123-1130, 2001.

I. Tamas, L. Klasson, B. Canback, A. K. Naslund, A. S. Eriksson et al., 50 million years of genomic stasis in endosymbiotic bacteria, Science, vol.296, pp.2376-2379, 2002.

M. L. Thao, L. Baumann, P. Baumann, and N. A. Moran, Endosymbionts (Buchnera) from the aphids Schizaphis graminum and Diuraphis noxia have different copy numbers of the plasmid containing the leucine biosynthetic genes, Curr Microbiol, vol.36, pp.238-240, 1998.

G. H. Thomas, J. Zucker, S. J. Macdonald, A. Sorokin, I. Goryanin et al., A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola, BMC Syst Biol, vol.3, p.24, 2009.

H. E. Umbarger, J. L. Neidhardt, K. L. Low, B. Magasanik, M. Schaechter et al., Biosynthesis of the branched chain amino acids, Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, pp.352-367, 1987.

J. Viñuelas, F. Calevro, D. Remond, J. Bernillon, Y. Rahbé et al., Conservation of the links between gene transcription and chromosomal organization in the highly reduced genome of Buchnera aphidicola, BMC Genomics, vol.8, p.143, 2007.

C. D. Von-dohlen and N. A. Moran, Molecular data support a rapid radiation of aphids in the Cretaceous and multiple origins of host alternation, Biol J Linn Soc, vol.71, pp.689-717, 2000.

J. J. Wernegreen, Genome evolution in bacterial endosymbionts of insects, Nat Rev Genet, vol.3, pp.850-861, 2002.

J. A. Whelan, N. B. Russell, and M. A. Whelan, A method for the absolute quantification of cDNA using realtime PCR, J Immunol Methods, vol.278, pp.261-269, 2003.

A. C. Wilson, P. D. Ashton, F. Calevro, H. Charles, S. Colella et al., Genomic insight into the amino acid relations of the pea aphid, Acyrthosiphon pisum, with its symbiotic bacterium Buchnera aphidicola, Insect Mol Biol, vol.19, pp.249-258, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00539196

H. Winter, G. Lohaus, and H. W. Heldt, Phloem transport of amino acids in relation to their cytosolic levels in barley leaves, Plant Physiol, vol.99, pp.996-1004, 1992.