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Sequential identification of boundary support parameters in a fluid-structure vascular model using patient image data

Abstract : Viscoelastic support has been previously established as a valuable modeling ingredient to represent the effect of surrounding tissues and organs in a fluid-structure vascular model. In this paper, we propose a complete methodological chain for the identification of the corresponding boundary support parameters, using patient image data. We consider distance maps of model to image contours as the discrepancy driving the data assimilation approach, which then relies on a combination of (1) state estimation based on the so-called SDF filtering method, designed within the realm of Luenberger observers and well adapted to handling measurements provided by image sequences, and (2) parameter estimation based on a reduced-order UKF filtering method which has no need for tangent operator computations and features natural parallelism to a high degree. Implementation issues are discussed, and we show that the resulting computational effectiveness of the complete estimation chain is comparable to that of a direct simulation. Furthermore, we demonstrate the use of this framework in a realistic application case involving hemodynamics in the thoracic aorta. The estimation of the boundary support parameters proves successful, in particular in that direct modeling simulations based on the estimated parameters are more accurate than with a previous manual expert calibration. This paves the way for complete patient-specific fluid-structure vascular modeling in which all types of available measurements could be used to estimate additional uncertain parameters of biophysical and clinical relevance.
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Contributor : Philippe Moireau Connect in order to contact the contributor
Submitted on : Tuesday, December 4, 2012 - 11:53:14 AM
Last modification on : Saturday, November 19, 2022 - 3:59:09 AM
Long-term archiving on: : Saturday, December 17, 2016 - 7:47:25 PM


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Philippe Moireau, Cristobal Bertoglio, Nan Xiao, C. Alberto Figueroa, Charles Taylor, et al.. Sequential identification of boundary support parameters in a fluid-structure vascular model using patient image data. Biomechanics and Modeling in Mechanobiology, 2012, 12 (3), pp.475-496. ⟨10.1007/s10237-012-0418-3⟩. ⟨hal-00760703⟩



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