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Intracranial solitary fibrous tumor: imaging findings.

Abstract : OBJECTIVE: To study the neuroimaging features of intracranial solitary fibrous tumors (ISFTs). MATERIALS AND METHODS: Retrospective study of neuroimaging features of 9 consecutive histopathologically proven ISFT cases. Location, size, shape, density, signal intensity and gadolinium uptake were studied at CT and MRI. Data collected from diffusion-weighted imaging (DWI) (3 patients), perfusion imaging and MR spectroscopy (2 patients), and DSA (4 patients) were also analyzed. RESULTS: The tumors most frequently arose from the intracranial meninges (7/9), while the other lesions were intraventricular. Tumor size ranged from 2.5 to 10 cm (mean=6.6 cm). They presented multilobular shape in 6/9 patients. Most ISFTs were heterogeneous (7/9) with areas of low T2 signal intensity that strongly enhanced after gadolinium administration (6/8). Erosion of the skull was present in about half of the cases (4/9). Components with decreased apparent diffusion coefficient were seen in 2/3 ISFTs on DWI. Spectroscopy revealed elevated peaks of choline and myo-inositol. MR perfusion showed features of hyperperfusion. CONCLUSION: ISFT should be considered in cases of extra-axial, supratentorial, heterogeneous, hypervascular tumor. Areas of low T2 signal intensity that strongly enhance after gadolinium injection are suggestive of this diagnosis. Restricted diffusion and elevated peak of myo-inositol may be additional valuable features.
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Submitted on : Thursday, February 28, 2013 - 6:16:24 PM
Last modification on : Friday, August 5, 2022 - 3:41:34 AM



Frédéric Clarençon, Fabrice Bonneville, Audrey Rousseau, Damien Galanaud, Michèle Kujas, et al.. Intracranial solitary fibrous tumor: imaging findings.. European Journal of Radiology, Elsevier, 2011, 80 (2), pp.387-394. ⟨10.1016/j.ejrad.2010.02.016⟩. ⟨hal-00795720⟩



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