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Conference papers

Lattice Boltzmann Method For Fast Patient-Specific Simulation of Liver Tumor Ablation from CT Images

Abstract : Radio-frequency ablation (RFA), the most widely used minimally invasive ablative therapy of liver cancer, is challenged by a lack of patient-specifi c planning. In particular, the presence of blood vessels and time varying thermal di ffusivity makes the prediction of the extent of the ablated tissue diffi cult. This may result in incomplete treatments and increased risk of recurrence. We propose a new model of the physical mechanisms involved in RFA of abdominal tumors based on Lattice Boltzmann Method to predict the extent of ablation given the probe location and the biological parameters. Our method relies on patient images, from which level set representations of liver geometry, tumor shape and vessels are extracted. Then a computational model of heat diff usion, cellular necrosis and blood flow through vessels and liver is solved to estimate the extent of ablated tissue. After quantitative verifi cations against an analytical solution, we apply our framework to 5 patients datasets which include pre- and post-operative CT images, yielding promising correlation between predicted and actual ablation extent (mean point to mesh errors of 8.7 mm). Implemented on graphics processing units, our method may enable RFA planning in clinical settings as it leads to near real-time computation: 1 minute of ablation is simulated in 1.14 minutes,which is almost 60 faster than standard fi nite element method.
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Submitted on : Wednesday, July 17, 2013 - 11:56:33 AM
Last modification on : Saturday, June 25, 2022 - 11:10:39 PM
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Chloé Audigier, Tommaso Mansi, Hervé Delingette, Saikiran Rapaka, Viorel Mihalef, et al.. Lattice Boltzmann Method For Fast Patient-Specific Simulation of Liver Tumor Ablation from CT Images. MICCAI - Medical Image Computing and Computer Assisted Intervention - 2013, Sep 2013, Nagoya, Japan. pp.323-330, ⟨10.1007/978-3-642-40760-4_41⟩. ⟨hal-00804147v2⟩



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