Early ADC changes in motor structures predict outcome of acute stroke better than lesion volume

Abstract : The lesion volume assessed from diffusion-weighted imaging (DWI) within the first six hours to first week following stroke onset has been proposed as a predictor of functional outcome in clinical studies. However, the prediction accuracy decreases when the DWI lesion volume is measured during the earliest stages of patient evaluation. In this study, our hypothesis was that the combination of lesion location (motor-related regions) and diffusivity measures (such as Apparent Diffusion Coefficient [ADC]) at the acute stage of stroke predict clinical outcome.
Keywords : ADC Stroke Outcome DWI
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Journal articles
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Submitted on : Wednesday, March 27, 2013 - 6:02:59 PM
Last modification on : Thursday, March 21, 2019 - 12:24:04 PM

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Charlotte Rosso, Olivier Colliot, Christian Pires, Christine Delmaire, Romain Valabrègue, et al.. Early ADC changes in motor structures predict outcome of acute stroke better than lesion volume. Journal de Neuroradiologie / Journal of Neuroradiology, Elsevier Masson, 2011, 38 (2), pp.105-12. ⟨10.1016/j.neurad.2010.05.001⟩. ⟨hal-00805381⟩

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