Phase space reconstruction of an experimental model of cardiac field potential in normal and arrhythmic conditions

Binbin Xu 1, * Sabir Jacquir 2 Gabriel Laurent 3 Jean-Marie Bilbault 2 Stéphane Binczak 2
* Corresponding author
1 GeoStat - Geometry and Statistics in acquisition data
Inria Bordeaux - Sud-Ouest
2 Le2i - Laboratoire Electronique, Informatique et Image [UMR6303]
3 Service de Cardiologie [CHU de Dijon]
Abstract : Cardiac arrhythmias are one of the most important death causes in the world. Compared to the numerical models, the experimental ones provide a more realistic tool to study the mechanisms of cardiac arrhythmias. The in vitro culture of cardiac cells developed on the Multi-Electrodes Array (MEA) constitutes a suitable model in this context. The extracellular field potential (EFP) acquired from the MEA can be used to measure the electrophysiological parameters of action potential. In this article, the stability of this experimental model is investigated using the phase space reconstruction in normal and in arrhythmia conditions. The results show that the embedding dimension of signal EFP changed slightly in both cases (normal conditions and arrhythmia). The parameter time lag $\tau$ in the normal conditions is lower than in the arrhythmia. The shape of attractors remains similar but disturbed in case of arrhythmia compared to the normal conditions.
Document type :
Conference papers
Complete list of metadatas

Cited literature [14 references]  Display  Hide  Download
https://hal.inria.fr/hal-00812198
Contributor : Binbin Xu <>
Submitted on : Friday, April 12, 2013 - 11:47:56 AM
Last modification on : Wednesday, September 12, 2018 - 1:27:59 AM
Long-term archiving on: Monday, April 3, 2017 - 4:25:02 AM

File

EMBC_2013_Binbin.pdf
Files produced by the author(s)

Identifiers

Collections

CNRS | INRIA | UNIV-BOURGOGNE | LE2I | ICB | UNIV-HESAM

Citation

Binbin Xu, Sabir Jacquir, Gabriel Laurent, Jean-Marie Bilbault, Stéphane Binczak. Phase space reconstruction of an experimental model of cardiac field potential in normal and arrhythmic conditions. EMBC 2013 - 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Jul 2013, Osaka, Japan. pp.3274 - 3277, ⟨10.1109/EMBC.2013.6610240⟩. ⟨hal-00812198⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

546

Files downloads

420

 

 

Contact

archive-ouverte@inria.fr