Fast Parameter Calibration of a Cardiac Electromechanical Model from Medical Images based on the Unscented Transform - Inria - Institut national de recherche en sciences et technologies du numérique Accéder directement au contenu
Article Dans Une Revue Biomechanics and Modeling in Mechanobiology Année : 2012

Fast Parameter Calibration of a Cardiac Electromechanical Model from Medical Images based on the Unscented Transform

Résumé

Patient-specific cardiac modelling can help in understanding pathophysiology and predict therapy planning. However, it requires to personalize the model geometry, kinematics, electrophysiology and mechanics. Calibration aims at providing proper initial values of parameters before performing the personalization stage which involves solving an inverse problem. We propose a fast automatic calibration method of the mechanical parameters of a complete electromechanical model of the heart based on a sensitivity analysis and the Unscented Transform algorithm. A new implementation of the complete Bestel-Clement-Sorine (BCS) cardiac model is also proposed, in a modular and efficient framework. A complete sensitivity analysis is performed that reveals which observations on the volume evolution are significant to characterize the global behaviour of the myocardium. We show that the calibration method gives satisfying results by optimizing up to 5 parameters of the BCS model in only one iteration. This method was evaluated synthetically as well as on 7 volunteers with a mean relative error from the real data of 10 %. This calibration is designed to replace manual parameter estimation as well as initialization steps that precede automatic personalization algorithms based on images.

Dates et versions

hal-00813847 , version 1 (16-04-2013)

Identifiants

Citer

Stéphanie Marchesseau, Hervé Delingette, Maxime Sermesant, Nicholas Ayache. Fast Parameter Calibration of a Cardiac Electromechanical Model from Medical Images based on the Unscented Transform. Biomechanics and Modeling in Mechanobiology, 2012, pp.1-17. ⟨10.1007/s10237-012-0446-z⟩. ⟨hal-00813847⟩
119 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More