An asymptotic two-layer monodomain model of cardiac electrophysiology in the atria: derivation and convergence * - Inria - Institut national de recherche en sciences et technologies du numérique Accéder directement au contenu
Article Dans Une Revue SIAM Journal on Applied Mathematics Année : 2017

An asymptotic two-layer monodomain model of cardiac electrophysiology in the atria: derivation and convergence *

Résumé

We investigate a dimensional reduction problem of a reaction-diffusion system related to cardiac electrophysiology modeling in the atria. The atrial tissues are very thin. The physical problem is then routinely stated on a two-dimensional manifold. However, some electrophysiological heterogeneities are located through the thickness of the tissue. Despite their biomedical significance, the usual dimensional reduction techniques tend to average and erase their influence on the two-dimensional propagation. We introduce a two-dimensional model with two coupled superimposed layers that allows us to take into account three-dimensional phenomena, but retains a reasonable computational cost. We present its mathematical derivation, show its convergence toward the three-dimensional model, and check numerically its convergence speed.
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Dates et versions

hal-00922717 , version 1 (30-12-2013)
hal-00922717 , version 2 (09-09-2014)
hal-00922717 , version 3 (11-10-2016)
hal-00922717 , version 4 (18-03-2017)

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Paternité - Partage selon les Conditions Initiales

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Yves Coudière, Jacques Henry, Simon Labarthe. An asymptotic two-layer monodomain model of cardiac electrophysiology in the atria: derivation and convergence *. SIAM Journal on Applied Mathematics, 2017, 77 (2), pp.409 - 429. ⟨10.1137/15M1016886⟩. ⟨hal-00922717v4⟩
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