Choosing Tractography Parameters to Improve Connectivity Mapping

Abstract : Diffusion-weighted imaging (DWI) is often used as a starting point for in vivo white matter (WM) connectivity to reconstruct potential WM pathways between brain areas. Tractography algorithms have many parameters which can influence reconstruction and connectivity. Various choices of parameters have been proposed. But how does one choose the best set of parameters? In this study, we varied three critical parameters while monitoring connectivity score using the Tractometer evaluation system on the International Symposium on Biomedical Imaging (ISBI) Challenge synthetic dataset. The three parameters were: * θ: The maximum deviation angle between two consecutive tractography steps. This addresses the hypothesis of smoothness of the WM pathways. * τ: The spherical function (SF) threshold. This aims at removing noisy propagation directions during the tractography process. * τ init : The initial SF threshold. This aims at removing initial noise at the seeds and to start tractography in a good tangent direction to the WM bundle.
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Communication dans un congrès
International Symposium on Magnetic Resonance in Medicine (ISMRM'14), May 2014, Milan, Italy. 2014
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https://hal.inria.fr/hal-00945992
Contributeur : Girard Gabriel <>
Soumis le : jeudi 13 février 2014 - 12:22:58
Dernière modification le : jeudi 11 janvier 2018 - 16:22:58
Document(s) archivé(s) le : mardi 13 mai 2014 - 23:30:11

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  • HAL Id : hal-00945992, version 1

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Girard Gabriel, Whittingstall Kevin, Rachid Deriche, Maxime Descoteaux. Choosing Tractography Parameters to Improve Connectivity Mapping. International Symposium on Magnetic Resonance in Medicine (ISMRM'14), May 2014, Milan, Italy. 2014. 〈hal-00945992〉

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