Skip to Main content Skip to Navigation
Journal articles

Neurogenesis in the Striatum of the Adult Human Brain.

Abstract : : In most mammals, neurons are added throughout life in the hippocampus and olfactory bulb. One area where neuroblasts that give rise to adult-born neurons are generated is the lateral ventricle wall of the brain. We show, using histological and carbon-14 dating approaches, that in adult humans new neurons integrate in the striatum, which is adjacent to this neurogenic niche. The neuronal turnover in the striatum appears restricted to interneurons, and postnatally generated striatal neurons are preferentially depleted in patients with Huntington's disease. Our findings demonstrate a unique pattern of neurogenesis in the adult human brain.
Complete list of metadata

https://hal.inria.fr/hal-00952021
Contributor : Samuel Bernard <>
Submitted on : Wednesday, February 26, 2014 - 10:04:36 AM
Last modification on : Monday, June 28, 2021 - 2:26:07 PM

Links full text

Identifiers

Citation

Aurélie Ernst, Kanar Alkass, Samuel Bernard, Mehran Salehpour, Shira Perl, et al.. Neurogenesis in the Striatum of the Adult Human Brain.. Cell, Elsevier, 2014, 156 (5), pp.1072-1083. ⟨10.1016/j.cell.2014.01.044⟩. ⟨hal-00952021⟩

Share

Metrics

Record views

772