Neurogenesis in the Striatum of the Adult Human Brain.

Abstract : : In most mammals, neurons are added throughout life in the hippocampus and olfactory bulb. One area where neuroblasts that give rise to adult-born neurons are generated is the lateral ventricle wall of the brain. We show, using histological and carbon-14 dating approaches, that in adult humans new neurons integrate in the striatum, which is adjacent to this neurogenic niche. The neuronal turnover in the striatum appears restricted to interneurons, and postnatally generated striatal neurons are preferentially depleted in patients with Huntington's disease. Our findings demonstrate a unique pattern of neurogenesis in the adult human brain.
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Cell, Elsevier, 2014, to be published. 〈10.1016/j.cell.2014.01.044〉
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https://hal.inria.fr/hal-00952021
Contributeur : Samuel Bernard <>
Soumis le : mercredi 26 février 2014 - 10:04:36
Dernière modification le : mercredi 11 avril 2018 - 01:50:45

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Aurélie Ernst, Kanar Alkass, Samuel Bernard, Mehran Salehpour, Shira Perl, et al.. Neurogenesis in the Striatum of the Adult Human Brain.. Cell, Elsevier, 2014, to be published. 〈10.1016/j.cell.2014.01.044〉. 〈hal-00952021〉

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