This paper focuses on developing new BiScO3-PbTiO3 (BS-PT) based piezoelectric ceramic transducers for high-temperature SHM applications. By controlling the PbO deficiency in the material system, we modify the lossy ferroelectric properties and enhance the piezoelectric responses from the intrinsic BS-PT. The new in-house fabricated piezoelectric transducers can maintain comparably high piezoelectric responses at temperatures up to 350ÁC continuously for at least 10 hours. The signals of the new BS-PT based piezoelectric transducers were tested and studied at different temperatures on metallic structures, and we observed a promising trend of obtaining stronger signals from the BS-PT transducers at higher temperatures. A new microfabrication method was developed to miniaturize and to mass-fabricate the piezoelectric transducers for potential applications on complex structures in extreme environments.