Learning fully-connected CRFs for blood vessel segmentation in retinal images

Abstract : In this work, we present a novel method for blood vessel segmentation in fundus images based on a discriminatively trained, fully connected conditional random field model. Retinal image analysis is greatly aided by blood vessel segmentation as the vessel structure may be considered both a key source of signal, e.g. in the diagnosis of diabetic retinopathy, or a nuisance, e.g. in the analysis of pigment epithelium or choroid related abnormalities. Blood vessel segmentation in fundus images has been considered extensively in the literature, but remains a challenge largely due to the desired structures being thin and elongated, a setting that performs particularly poorly using standard segmentation priors such as a Potts model or total variation. In this work, we overcome this difficulty using a discriminatively trained conditional random field model with more expressive potentials. In particular, we employ recent results enabling extremely fast inference in a fully connected model. We find that this rich but computationally efficient model family, combined with principled discriminative training based on a structured output support vector machine yields a fully automated system that achieves results statistically indistinguishable from an expert human annotator. Implementation details are available at http://pages.saclay.inria.fr/matthew.blaschko/projects/retina/.
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https://hal.inria.fr/hal-01024226
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José Ignacio Orlando, Matthew Blaschko. Learning fully-connected CRFs for blood vessel segmentation in retinal images. Medical Image Computing and Computer Assisted Intervention (MICCAI), Sep 2014, Boston, United States. ⟨10.1007/978-3-319-10404-1_79⟩. ⟨hal-01024226⟩

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