Java Protein Dossier: a novel web-based data visualization tool for comprehensive analysis of protein structure

Abstract : Java Protein Dossier (JPD) is a new concept, database and visualization tool providing one of the largest collections of the physicochemical parameters describing proteins' structure, stability, function and interaction with other macromolecules. By collecting as many descriptors/parameters as possible within a single database, we can achieve a better use of the available data and information. Furthermore, data grouping allows us to generate different para-meters with the potential to provide new insights into the sequence–structure–function relationship. In J PD, residue selection can be performed according to multiple criteria. J PD can simultaneously display and analyze all the physicochemical parameters of any pair of structures, using precalculated structural alignments, allowing direct parameter comparison at corresponding amino acid positions among homolo-gous structures. In order to focus on the physico-chemical (and consequently pharmacological) profile of proteins, visualization tools (showing the structure and structural parameters) also had to be optimized. Our response to this challenge was the use of Java technology with its exceptional level of interactivity. JPD is freely accessible (within the Gold Sting Suite) at http://sms.cbi.cnptia.embrapa.br/ (Option: Java Protein Dossier)
Type de document :
Article dans une revue
Nucleic Acids Research, Oxford University Press, 2004, Web Server issue, 32, pp.W595-W601. 〈10.1093/nar/gkh480〉
Liste complète des métadonnées

Littérature citée [22 références]  Voir  Masquer  Télécharger

https://hal.inria.fr/hal-01092990
Contributeur : Christian Baudet <>
Soumis le : mardi 9 décembre 2014 - 21:09:23
Dernière modification le : jeudi 14 décembre 2017 - 14:12:02
Document(s) archivé(s) le : mardi 10 mars 2015 - 12:26:21

Fichier

Nucl. Acids Res.-2004-Neshich-...
Fichiers éditeurs autorisés sur une archive ouverte

Identifiants

Citation

Goran Neshich, Walter Rocchia, Adauto Mancini, Michel Yamagishi, Paula Kuser, et al.. Java Protein Dossier: a novel web-based data visualization tool for comprehensive analysis of protein structure. Nucleic Acids Research, Oxford University Press, 2004, Web Server issue, 32, pp.W595-W601. 〈10.1093/nar/gkh480〉. 〈hal-01092990〉

Partager

Métriques

Consultations de la notice

86

Téléchargements de fichiers

71