Morphological Analysis and Feature Extraction of Neurons from Mouse Cortices Multiscale 3D Microscopic Images

Alexis Zubiolo 1 Kawssar Harb 2 Michèle Studer 2 Eric Debreuve 3 Xavier Descombes 1
1 MORPHEME - Morphologie et Images
CRISAM - Inria Sophia Antipolis - Méditerranée , IBV - Institut de Biologie Valrose : U1091, Laboratoire I3S - SIS - Signal, Images et Systèmes
Abstract : In this paper, we propose a framework to analyze the morphology of mouse neurons in the layer V of the cortex from 3D microscopic images. We are given 8 sets of images, each of which is composed of a 10x image showing the whole neurons, and a few (2 to 5) 40x images focusing on the somas. The framework consists in segmenting the neurons on both types of images to compute a set of specific morphological features, and in matching the neurons in the 40x images to their counterparts in the 10x images to combine the features we obtained, in a fully automatic fashion.
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Alexis Zubiolo, Kawssar Harb, Michèle Studer, Eric Debreuve, Xavier Descombes. Morphological Analysis and Feature Extraction of Neurons from Mouse Cortices Multiscale 3D Microscopic Images. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2015), IEEE Engineering in Medicine and Biology Society (EMBS), Aug 2015, Milan, Italy. ⟨10.1109/EMBC.2015.7320118⟩. ⟨hal-01176966⟩

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