Propagation of Myocardial Fibre Architecture Uncertainty on Electromechanical Model Parameter Estimation: A Case Study

Roch Molléro 1 Dominik Neumann 2, 3 Marc-Michel Rohé 1 Manasi Datar 3 Herve Lombaert 1 Nicholas Ayache 1 Dorin Comaniciu 4 Olivier Ecabert 3 Marcello Chinali 5 Gabriele Rinelli 5 Xavier Pennec 1 Maxime Sermesant 1 Tommaso Mansi 4
1 ASCLEPIOS - Analysis and Simulation of Biomedical Images
CRISAM - Inria Sophia Antipolis - Méditerranée
2 Pattern Recognition Lab [Erlangen-Nuremberg]
3 Siemens Corporate Technology, Imaging and Computer Vision, Erlangen
4 Siemens Corporate Research [Princeton]
5 IRCCS Ospedale Pediatrico Bambino Gesù [Roma]
Abstract : Computer models of the heart are of increasing interest for clinical applications due to their discriminative and predictive power. However the personalisation step to go from a generic model to a patient-specific one is still a scientific challenge. In particular it is still difficult to quantify the uncertainty on the estimated parameters and predicted values. In this manuscript we present a new pipeline to evaluate the impact of fibre uncertainty on the personalisation of an electromechanical model of the heart from ECG and medical images. We detail how we estimated the variability of the fibre architecture among a given population and how the uncertainty generated by this variability impacts the following personalisation. We first show the variability of the personalised simulations, with respect to the principal variations of the fibres. Then discussed how the variations in this (small) healthy population of fibres impact the parameters of the personalised simulations.
Type de document :
Communication dans un congrès
Functional Imaging and Modeling of the Heart, LNCS., Jun 2015, Maastricht, Netherlands. pp. 448-456, 2015, 8th International Conference, FIMH 2015, Maastricht, The Netherlands, June 25-27, 2015. Proceedings. 〈http://www.fimh2015.org/〉. 〈10.1007/978-3-319-20309-6_51〉
Liste complète des métadonnées

Littérature citée [16 références]  Voir  Masquer  Télécharger
https://hal.inria.fr/hal-01241896
Contributeur : Roch Mollero <>
Soumis le : vendredi 11 décembre 2015 - 10:39:45
Dernière modification le : mercredi 30 mai 2018 - 13:56:03
Document(s) archivé(s) le : samedi 29 avril 2017 - 10:57:20

Fichier

FIMH2015_UncertaintyPropagatio...
Fichiers produits par l'(les) auteur(s)

Identifiants

Collections

INRIA | SOFA | UNIV-COTEDAZUR

Citation

Roch Molléro, Dominik Neumann, Marc-Michel Rohé, Manasi Datar, Herve Lombaert, et al.. Propagation of Myocardial Fibre Architecture Uncertainty on Electromechanical Model Parameter Estimation: A Case Study. Functional Imaging and Modeling of the Heart, LNCS., Jun 2015, Maastricht, Netherlands. pp. 448-456, 2015, 8th International Conference, FIMH 2015, Maastricht, The Netherlands, June 25-27, 2015. Proceedings. 〈http://www.fimh2015.org/〉. 〈10.1007/978-3-319-20309-6_51〉. 〈hal-01241896〉

Exporter

BibTeX TEI DC DCterms EndNote

Partager

Métriques

Consultations de la notice

327

Téléchargements de fichiers

261

Contact


archive-ouverte@inria.fr