Abstract : —The development of Cyber Physical Systems (CPS) requires to model both the cyber (i.e., digital) parts, the physical parts and the interaction between them. The state of the practice in such domain usually involves different stakeholders, which use dedicated modeling languages tailored syntactically and semantically to their domain. Functional Mock-up Interface (FMI) is a recent standard, which provides technical facilities to enable the co-simulation among the different dedicated modeling languages. In this context, this paper investigates how discrete-event models of the cyber part are supported by FMI standard for co-simulation. Two main results are presented: 1) how SystemC models can be integrated into the FMI environment and 2) FMI limitations for the efficient use of discrete-event models in co-simulation. Both results are illustrated by using a simple but illustrative use case mixing models in SystemC (for the cyber part) and Modelica (for the physical part).