Classifying the spatiotemporal patterns within stage II retinal waves through dynamical systems analysis

Abstract : Retinal waves are bursts of activity occurring spontaneously in the developing retina of vertebrate species, contributing to the shaping of the visual system organization. They are characterized by localized groups of neurons becoming simultaneously active, initiated at random points. Based on our previous modelling work [1], we now propose a classification of stage II retinal waves patterns as a function of acetylcholine coupling strength and a possible mechanism for waves generation. Our model predicts that spatiotemporal patterns evolve upon maturation or pharmacological manipulation and that there is a regime of cholinergic coupling, only for which, waves are characterized by power-law distributions.
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Dernière modification le : vendredi 31 août 2018 - 09:13:20
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Dora Karvouniari, Lionel Gil, Olivier Marre, Serge Picaud, Bruno Cessac. Classifying the spatiotemporal patterns within stage II retinal waves through dynamical systems analysis. Bernstein Conference 2016, Sep 2016, Berlin, Germany. 2016. 〈hal-01371596〉

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