Medial vascular calcification revisited: review and perspectives

Abstract : Vascular calcifications (VCs) are actively regulated biological processes associated with crystallization of hydroxyapatite in the extracellular matrix and in cells of the media (VCm) or intima (VCi) of the arterial wall. Both patterns of VC often coincide and occur in patients with type II diabetes, chronic kidney disease, and other less frequent disorders; VCs are also typical in senile degeneration. In this article, we review the current state of knowledge about the pathology, molecular biology, and nosology of VCm, expand on potential mechanisms responsible for poor prognosis, and expose some of the directions for future research in this area.
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European Heart Journal, Oxford University Press (OUP): Policy B, 2014, 35, pp.1515 - 1525. 〈10.1093/eurheartj/ehu163〉
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Soumis le : jeudi 20 octobre 2016 - 15:47:25
Dernière modification le : lundi 10 septembre 2018 - 14:20:01

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Peter Lanzer, Manfred Boehm, Victor Sorribas, Marc Thiriet, Jan Janzen, et al.. Medial vascular calcification revisited: review and perspectives. European Heart Journal, Oxford University Press (OUP): Policy B, 2014, 35, pp.1515 - 1525. 〈10.1093/eurheartj/ehu163〉. 〈hal-01384964〉

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