The university course on statistical methods in health at the Bordeaux School of Public Health, University of Bordeaux, has been run as an Open and Distance Learning (ODL) program since 2004 on the basics of statistical reasoning in the health field. The course is mainly for professionals. In more than ten years, about 1,000 people have been trained with over a third coming from sub-Saharan Africa. The program aims to meet a growing demand for statistical training from professionals from the south whose mobility is limited. Each year a satisfaction survey is sent to students with a view to improving the program. Even though participation in the survey is anonymous and not compulsory, it is a valuable source of comments and ideas. These have led to innovative pedagogical practices such as “tutored exercises” with individual correction, the use of new statistical software, summary sheets and flipped classrooms. However, benchmarking of the program has shown that more could be done. Teaching strategies should evolve within the framework of distance learning in terms of content, form and interactivity. This article discusses the development of these new educational strategies from their inception as well as future projects.