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A Portable Impedance Detector of Interdigitated Array Microelectrode for Rapid Detection of Avian Influenza Virus

Abstract : Impedance biosensors are featured with fast detection, easy operation and low-cost, and have been reported in the detection of avian influenza viruses, foodborne pathogens and pesticide residues. Based on our previous research on impedance biosensors for rapid detection of avian influenza virus, a portable impedance detector was redesigned using an S3C2440AL ARM9 microprocessor and an improved AD5933 impedance converter to meet the higher requirements on frequency and magnitude in impedance measurement from the new interdigitated array microelectrodes, which were redesigned for reducing the cost and improving the produce quality. The impedance measurement range is 50 Ω-1MΩ and the frequency response range is 100 Hz-100 kHz. Compared to commercial E4980A precision LCR meter on the measurements of solid-state resistor, solid-state equivalent circuit of the electrode and avian influenza virus test, this impedance detector showed a relative error of less than 5% at the characteristic frequency of 100 Hz and a standard deviation of less than 5% in parallel tests. Besides, a linear relationship between impedance change ΔZ and the concentration of avian influenza virus ranging from 2− 1 HAU/ 50 μl to 24 HAU/ 50 μl was found.
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Xiaohong Wang, Zhuo Zhao, Yuhe Wang, Jianhan Lin. A Portable Impedance Detector of Interdigitated Array Microelectrode for Rapid Detection of Avian Influenza Virus. 8th International Conference on Computer and Computing Technologies in Agriculture (CCTA), Sep 2014, Beijing, China. pp.247-256, ⟨10.1007/978-3-319-19620-6_31⟩. ⟨hal-01420240⟩



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