Modeling Cystic Fibrosis and Mucociliary Clearance

Abstract : This chapter considers the investigation of airway clearance efficiency and dysfunction using rheological measurements, modeling and simulations of mucus flows. The work is mainly dedicated to the respiratory epithelium dysfunction subsequently to the consumption of cilia-inhibiting drugs (e.g. nicotine) or viral and/or bacterial infections, and cystic fibrosis, although many respiratory diseases are associated with an altered mucus transport.
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Dominique Anne-Archard, Robin Chatelin, Marlène Murris-Espin, David Sanchez, Marc Thiriet, et al.. Modeling Cystic Fibrosis and Mucociliary Clearance. Sid M. Becker. Modeling of microscale transport in biological processes, Academic Press, pp.113-154, 2017, 978-0-12-804595-4. ⟨10.1016/B978-0-12-804595-4.00005-5⟩. ⟨hal-01476216⟩

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