Molecular architecture of the neuromuscular junction, Muscle & Nerve, vol.10, issue.4, pp.445-61, 2006. ,
DOI : 10.1002/mus.20440
The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo, Cell, vol.85, issue.4, pp.501-512, 1996. ,
DOI : 10.1016/S0092-8674(00)81251-9
Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies, Nature Medicine, vol.7, issue.3, pp.365-368, 2001. ,
DOI : 10.1038/85520
Crystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSK, Journal of Molecular Biology, vol.393, issue.1, pp.1-9, 2009. ,
DOI : 10.1016/j.jmb.2009.07.091
Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK, Journal of Molecular Biology, vol.364, issue.3, pp.424-433, 2006. ,
DOI : 10.1016/j.jmb.2006.09.019
Agrin Acts via a MuSK Receptor Complex, Cell, vol.85, issue.4, pp.513-523, 1996. ,
DOI : 10.1016/S0092-8674(00)81252-0
URL : http://doi.org/10.1016/s0092-8674(00)81252-0
Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK, Cell, vol.135, issue.2, pp.334-342, 2008. ,
DOI : 10.1016/j.cell.2008.10.002
The Muscle Protein Dok-7 Is Essential for Neuromuscular Synaptogenesis, Science, vol.312, issue.5781, pp.1802-1805, 2006. ,
DOI : 10.1126/science.1127142
Advances in Homology Protein Structure Modeling, Current Protein & Peptide Science, vol.7, issue.3, pp.217-227, 2006. ,
DOI : 10.2174/138920306777452312
Swiss-Prot: Juggling between evolution and stability, Briefings in Bioinformatics, vol.5, issue.1, pp.39-55, 2004. ,
DOI : 10.1093/bib/5.1.39
Tools for comparative protein structure modeling and analysis, Nucleic Acids Research, vol.31, issue.13, pp.3375-3380, 2003. ,
DOI : 10.1093/nar/gkg543
URL : http://doi.org/10.1093/nar/gkg543
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling, Bioinformatics, vol.22, issue.2, pp.195-201, 2006. ,
DOI : 10.1093/bioinformatics/bti770
Basic local alignment search tool, Journal of Molecular Biology, vol.215, issue.3, pp.403-410, 1990. ,
DOI : 10.1016/S0022-2836(05)80360-2
The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction, Protein Science, vol.6, issue.10, pp.2174-2183, 2007. ,
DOI : 10.1110/ps.072802707
P: Crystallization and structure determonation of goat lactoferrin at 4.0A resolution: A new form of packing in lactoferrins with a high solvent content in crystals, Indian J.Biochem.Biophys, vol.39, pp.16-21, 2002. ,
The PyMOL Molecular Graphics System DeLano Scientific, 2002. ,
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice, Nucleic Acids Research, vol.22, issue.22, pp.4673-4680, 1994. ,
DOI : 10.1093/nar/22.22.4673
The Amber biomolecular simulation programs, Journal of Computational Chemistry, vol.124, issue.16, pp.1668-1688, 2005. ,
DOI : 10.1002/jcc.20290
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1989667
H++: a server for estimating pKas and adding missing hydrogens to macromolecules, Nucleic Acids Research, vol.33, issue.Web Server, pp.368-371, 2005. ,
DOI : 10.1093/nar/gki464
A 2nd Generation Force-Field for the Simulation of Proteins,Nucleic-Acids, and Organic-Molecules, Journal of the American Chemical Society, issue.19, pp.1175179-5197, 1995. ,
Comparison of multiple Amber force fields and development of improved protein backbone parameters, Proteins: Structure, Function, and Bioinformatics, vol.43, issue.3, pp.712-725, 2006. ,
DOI : 10.1002/prot.21123
Theory and applications of the generalized born solvation model in macromolecular simulations, Biopolymers, vol.2, issue.4, pp.275-291, 2000. ,
DOI : 10.1002/1097-0282(2000)56:4<275::AID-BIP10024>3.0.CO;2-E
Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models, Journal of Computational Chemistry, vol.114, issue.8, pp.952-962, 1992. ,
DOI : 10.1002/jcc.540130805
Molecular Dynamics Simulations on Solvated Biomolecular Systems: The Particle Mesh Ewald Method Leads to Stable Trajectories of DNA, RNA, and Proteins, Journal of the American Chemical Society, vol.117, issue.14, pp.117-4193, 1995. ,
DOI : 10.1021/ja00119a045
Molecular dynamics with coupling to an external bath, The Journal of Chemical Physics, vol.15, issue.8, pp.81-3684, 1984. ,
DOI : 10.1039/fs9821700055
Comparison of simple potential functions for simulating liquid water, The Journal of Chemical Physics, vol.79, issue.2, pp.926-935, 1983. ,
DOI : 10.1016/0009-2614(80)85344-9
VMD: Visual molecular dynamics, Journal of Molecular Graphics, vol.14, issue.1, pp.33-38, 1996. ,
DOI : 10.1016/0263-7855(96)00018-5
Ribbon representation of MuSK protein. The image above shows the gradual " unpacking " of the CRD domain and the rotation of the Ig domains. The image was created using the VMD ,