M. E. Samuels and J. M. Friedman, Genetic Mosaics and the Germ Line Lineage, Genes, vol.112, issue.4, pp.216-237, 2015.
DOI : 10.1002/humu.22757

URL : http://doi.org/10.3390/genes6020216

R. P. Erickson, Recent advances in the study of somatic mosaicism and diseases other than cancer, Current Opinion in Genetics & Development, vol.26, pp.73-78, 2014.
DOI : 10.1016/j.gde.2014.06.001

C. C. Laurie, Detectable clonal mosaicism from birth to old age and its relationship to cancer, Nature Genetics, vol.24, issue.6, pp.642-650, 2012.
DOI : 10.1016/j.ajhg.2010.06.002

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366033

E. Ruark, Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer, Nature, vol.5, issue.7432, pp.406-410, 2013.
DOI : 10.1002/gepi.1370050611

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759028

S. Behjati, Genome sequencing of normal cells reveals developmental lineages and mutational processes, Nature, vol.13, issue.7518, pp.422-425, 2014.
DOI : 10.1038/nrg3186

E. Vanneste, Chromosome instability is common in human cleavage-stage embryos, Nature Medicine, vol.2, issue.5, pp.577-583, 2009.
DOI : 10.1038/nm.1924

L. B. Alexandrov, Signatures of mutational processes in human cancer, Nature, vol.27, issue.7463, pp.415-421, 2013.
DOI : 10.1093/bioinformatics/btr354

E. Oron and N. Ivanova, Cell fate regulation in early mammalian development, Physical Biology, vol.9, issue.4, p.45002, 2012.
DOI : 10.1088/1478-3975/9/4/045002

G. Genovese, Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence, New England Journal of Medicine, vol.371, issue.26, pp.2477-2487, 2014.
DOI : 10.1056/NEJMoa1409405

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290021

S. Jaiswal, Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes, New England Journal of Medicine, vol.371, issue.26, pp.2488-2498, 2014.
DOI : 10.1056/NEJMoa1408617

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306669

M. Xie, Age-related mutations associated with clonal hematopoietic expansion and malignancies, Nature Medicine, vol.15, issue.12, pp.1472-1478, 2014.
DOI : 10.1038/gim.2013.92

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313872

A. W. Bruce and M. Zernicka-goetz, Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate, Current Opinion in Genetics & Development, vol.20, issue.5, pp.485-491, 2010.
DOI : 10.1016/j.gde.2010.05.006

B. Plusa, The first cleavage of the mouse zygote predicts the blastocyst axis, Nature, vol.32, issue.7031, pp.391-395, 2005.
DOI : 10.1038/nature02595

M. Zernicka-goetz, S. A. Morris, and A. W. Bruce, Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo, Nature Reviews Genetics, vol.284, issue.7, pp.467-477, 2009.
DOI : 10.1038/nrg2564

N. Plachta, T. Bollenbach, S. Pease, S. E. Fraser, and P. Pantazis, Oct4 kinetics predict cell lineage patterning in the early mammalian embryo, Nature Cell Biology, vol.9, issue.2, pp.117-123, 2011.
DOI : 10.1016/j.cell.2005.08.040

I. Bedzhov, S. J. Graham, C. Y. Leung, and M. Zernicka-goetz, Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.9, issue.15, p.20130538, 2014.
DOI : 10.1101/gad.9.15.1883

S. A. Morris, Y. Guo, and M. Zernicka-goetz, Developmental Plasticity Is Bound by Pluripotency and the Fgf and Wnt Signaling Pathways, Cell Reports, vol.2, issue.4, pp.756-765, 2012.
DOI : 10.1016/j.celrep.2012.08.029

URL : http://doi.org/10.1016/j.celrep.2012.08.029

K. Hardy, A. H. Handyside, and R. M. Winston, The human blastocyst: cell number, death and allocation during late preimplantation development in vitro, Development, vol.107, pp.597-604, 1989.

P. Strnad, Inverted light-sheet microscope for imaging mouse pre-implantation development, Nature Methods, vol.107, issue.2, pp.139-142, 2016.
DOI : 10.1038/lsa.2014.46

R. Rahbari, Timing, rates and spectra of human germline mutation, Nature Genetics, vol.20, issue.2, pp.126-133, 2016.
DOI : 10.1111/j.1558-5646.2011.01337.x

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731925

R. Acuna-hidalgo, Post-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic Variation, The American Journal of Human Genetics, vol.97, issue.1, pp.67-74, 2015.
DOI : 10.1016/j.ajhg.2015.05.008

A. Y. Huang, Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals, Cell Research, vol.86, issue.11, pp.1311-1327, 2014.
DOI : 10.1038/nature09534

G. M. Dal, Early postzygotic mutations contribute to de novo variation in a healthy monozygotic twin pair, Journal of Medical Genetics, vol.479, issue.7, pp.455-459, 2014.
DOI : 10.1038/nature10531

M. Lynch, Rate, molecular spectrum, and consequences of human mutation, Proc. Natl Acad. Sci. USA, pp.961-968, 2010.
DOI : 10.1038/416624a

I. Martincorena and P. J. Campbell, Somatic mutation in cancer and normal cells, Science, vol.502, issue.7155, pp.1483-1489, 2015.
DOI : 10.1038/nature12634

S. Nik-zainal, Landscape of somatic mutations in 560 breast cancer whole-genome sequences, Nature, vol.14, issue.7605, pp.47-54, 2016.
DOI : 10.1093/bioinformatics/btq170

URL : https://hal.archives-ouvertes.fr/hal-01388447

H. Li and R. Durbin, Fast and accurate long-read alignment with Burrows?Wheeler transform, Bioinformatics, vol.26, issue.5, pp.589-595, 2010.
DOI : 10.1093/bioinformatics/btp698

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828108

P. J. Stephens, The landscape of cancer genes and mutational processes in breast cancer, Nature, vol.135, pp.400-404, 2012.
DOI : 10.2307/2344614

D. C. Koboldt, VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing, Genome Research, vol.22, issue.3, pp.568-576, 2012.
DOI : 10.1101/gr.129684.111

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290792

H. Li, The Sequence Alignment/Map format and SAMtools, Bioinformatics, vol.25, issue.16, pp.2078-2079, 2009.
DOI : 10.1093/bioinformatics/btp352

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723002

S. Nik-zainal, The Life History of 21 Breast Cancers, Cell, vol.149, issue.5, pp.994-1007, 2012.
DOI : 10.1016/j.cell.2012.04.023

P. Van-loo, Allele-specific copy number analysis of tumors, Proc. Natl Acad. Sci. USA, pp.16910-16915, 2010.
DOI : 10.1200/JCO.2008.18.1370

J. T. Robinson, Integrative genomics viewer, Nature Biotechnology, vol.306, issue.1, pp.24-26, 2011.
DOI : 10.1093/bioinformatics/btp472

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346182

M. E. Skinner, A. V. Uzilov, L. D. Stein, C. J. Mungall, and I. H. Holmes, JBrowse: A next-generation genome browser, Genome Research, vol.19, issue.9, pp.1630-1638, 2009.
DOI : 10.1101/gr.094607.109

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752129

H. Holstege, Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis, Genome Research, vol.24, issue.5, pp.733-742, 2014.
DOI : 10.1101/gr.162131.113

Y. Marikawa and V. B. Alarcón, Establishment of trophectoderm and inner cell mass lineages in the mouse embryo, Molecular Reproduction and Development, vol.221, issue.11, pp.1019-1032, 2009.
DOI : 10.1016/j.fertnstert.2008.09.023

L. Laurent, Dynamic changes in the human methylome during differentiation, Genome Research, vol.20, issue.3, pp.320-331, 2010.
DOI : 10.1101/gr.101907.109