Model-based generation of large databases of cardiac images: synthesis of pathological cine MR sequences from real healthy cases - Archive ouverte HAL Access content directly
Journal Articles IEEE Transactions on Medical Imaging Year : 2018

Model-based generation of large databases of cardiac images: synthesis of pathological cine MR sequences from real healthy cases

(1, 2, 3) , (2, 4) , (2, 4) , (2, 4)
1
2
3
4

Abstract

Collecting large databases of annotated medical images is crucial for the validation and testing of feature extraction, statistical analysis and machine learning algorithms. Recent advances in cardiac electromechanical modeling and image synthesis provided a framework to generate synthetic images based on realistic mesh simulations. Nonetheless, their potential to augment an existing database with large amounts of synthetic cases requires further investigation. We build upon these works and propose a revised scheme for synthesizing pathological cardiac sequences from real healthy sequences. Our new pipeline notably involves a much easier registration problem to reduce potential artifacts, and takes advantage of mesh correspondences to generate new data from a given case without additional registration. The output sequences are thoroughly examined in terms of quality and usability on a given application: the assessment of myocardial viability, via the generation of 465 synthetic cine MR sequences (15 healthy and 450 with pathological tissue viability [random location, extent and grade, up to myocardial infarct]). We demonstrate that our methodology (i) improves state-of-the-art algorithms in terms of realism and accuracy of the simulated images, and (ii) is well-suited for the generation of large databases at small computational cost.
Fichier principal
Vignette du fichier
jDuchateau_TMI_2017_FINAL.pdf (8.45 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-01533788 , version 1 (06-06-2017)

Identifiers

Cite

Nicolas Duchateau, Maxime Sermesant, Hervé Delingette, Nicholas Ayache. Model-based generation of large databases of cardiac images: synthesis of pathological cine MR sequences from real healthy cases. IEEE Transactions on Medical Imaging, 2018, 37, pp.755-766. ⟨10.1109/TMI.2017.2714343⟩. ⟨hal-01533788⟩
375 View
435 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More