Dosage compensation and sex-specific epigenetic landscape of the X chromosome in the pea aphid.

Résumé : Heterogametic species display a differential number of sex chromosomes resulting in imbalanced transcription levels for these chromosomes between males and females. To correct this disequilibrium, dosage compensation mechanisms involving gene expression and chromatin accessibility regulations have emerged throughout evolution. In insects, these mechanisms have been extensively characterized only in Drosophila but not in insects of agronomical importance. Aphids are indeed major pests of a wide range of crops. Their remarkable ability to switch from asexual to sexual reproduction during their life cycle largely explains the economic losses they can cause. As heterogametic insects, male aphids are X0, while females (asexual and sexual) are XX.
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Epigenetics & Chromatin, BioMed Central, 2017, 10 (1), pp.1-17. 〈10.1186/s13072-017-0137-1〉
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Soumis le : mercredi 20 juin 2018 - 13:46:25
Dernière modification le : vendredi 29 juin 2018 - 10:42:43

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Gautier Richard, Fabrice Legeai, Nathalie Prunier-Leterme, Anthony Bretaudeau, Denis Tagu, et al.. Dosage compensation and sex-specific epigenetic landscape of the X chromosome in the pea aphid.. Epigenetics & Chromatin, BioMed Central, 2017, 10 (1), pp.1-17. 〈10.1186/s13072-017-0137-1〉. 〈hal-01555242〉

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