Evaluation of a Rapid Anisotropic Model for ECG Simulation - Archive ouverte HAL Access content directly
Journal Articles Frontiers in Physiology Year : 2017

Evaluation of a Rapid Anisotropic Model for ECG Simulation

(1, 2) , (2, 3) , (2, 4, 5) , (2, 6) , (7, 2) , (1, 2)
1
2
3
4
5
6
7

Abstract

State-of-the-art cardiac electrophysiology models that are able to deliver physiologically motivated activation maps and electrocardiograms (ECGs) can only be solved on high-performance computing architectures. This makes it nearly impossible to adopt such models in clinical practice. ECG imaging tools typically rely on simplified models, but these neglect the anisotropic electric conductivity of the tissue in the forward problem. Moreover, their results are often confined to the heart-torso interface. We propose a forward model that fully accounts for the anisotropic tissue conductivity and produces the standard 12-lead ECG in a few seconds. The activation sequence is approximated with an eikonal model in the 3d myocardium, while the ECG is computed with the lead-field approach. Both solvers were implemented on graphics processing units and massively parallelized. We studied the numerical convergence and scalability of the approach. We also compared the method to the bidomain model in terms of ECGs and activation maps, using a simplified but physiologically motivated geometry and 6 patient-specific anatomies. The proposed methods provided a good approximation of activation maps and ECGs computed with a bidomain model, in only a few seconds. Both solvers scaled very well to high-end hardware. These methods are suitable for use in ECG imaging methods, and may soon become fast enough for use in interactive simulation tools.
Fichier principal
Vignette du fichier
pezzuto-rapidecg.pdf (4.08 Mo) Télécharger le fichier
Origin : Publisher files allowed on an open archive
Loading...

Dates and versions

hal-01567861 , version 1 (24-07-2017)

Identifiers

Cite

Simone Pezzuto, Peter Kalavsky, Mark Potse, Frits W Prinzen, Angelo Auricchio, et al.. Evaluation of a Rapid Anisotropic Model for ECG Simulation. Frontiers in Physiology, 2017, 8, pp.265. ⟨10.3389/fphys.2017.00265⟩. ⟨hal-01567861⟩

Collections

CNRS INRIA INRIA2
486 View
121 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More