A Three-Dimensional Computational Model of Action Potential Propagation Through a Network of Individual Cells

Pierre-Elliott Bécue 1, 2, 3 Mark Potse 1, 2 Yves Coudière 1, 2, 3
2 CARMEN - Modélisation et calculs pour l'électrophysiologie cardiaque
IMB - Institut de Mathématiques de Bordeaux, Inria Bordeaux - Sud-Ouest, IHU-LIRYC
Abstract : It has been suggested in the literature that a disorganization of cardiac tissue at the cellular scale may affect the propagation of the action potential (AP) at the tissue scale, and may play a role in arrhythmia. We developed a model of the myocardium at sub-cellular resolution in which the intracellular space, the cell membrane, and the extracellular space are discretized individually. We tested this approach on small, hand-crafted two- and three-dimensional networks of cells.
Liste complète des métadonnées

https://hal.inria.fr/hal-01592178
Contributeur : Pierre-Elliott Bécue <>
Soumis le : vendredi 22 septembre 2017 - 17:29:59
Dernière modification le : jeudi 15 mars 2018 - 22:16:03
Document(s) archivé(s) le : samedi 23 décembre 2017 - 14:25:39

Identifiants

  • HAL Id : hal-01592178, version 1

Collections

Citation

Pierre-Elliott Bécue, Mark Potse, Yves Coudière. A Three-Dimensional Computational Model of Action Potential Propagation Through a Network of Individual Cells. Computing in Cardiology 2017, Sep 2017, Rennes, France. pp.1-4, 〈http://www.cinc.org/〉. 〈hal-01592178〉

Partager

Métriques

Consultations de la notice

288

Téléchargements de fichiers

52