A Density-Driven Method for the Placement of Biological Cells Over Two-Dimensional Manifolds

Nicolas P. Rougier 1
1 Mnemosyne - Mnemonic Synergy
LaBRI - Laboratoire Bordelais de Recherche en Informatique, Inria Bordeaux - Sud-Ouest, IMN - Institut des Maladies Neurodégénératives [Bordeaux]
Abstract : We introduce a graphical method originating from the computer graphics domain that is used for the arbitrary placement of cells over a two-dimensional manifold. Using a bitmap image whose luminance provides cell density, this method guarantees a discrete distribution of the positions of the cells respecting the local density. This method scales to any number of cells, allows one to specify arbitrary enclosing shapes and provides a scalable and versatile alternative to the more classical assumption of a uniform spatial distribution. The method is illustrated on a discrete homogeneous neural field, on the distribution of cones and rods in the retina and on the neural density of a flattened piece of cortex.
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https://hal.inria.fr/hal-01617732
Contributor : Nicolas P. Rougier <>
Submitted on : Thursday, March 29, 2018 - 9:19:53 AM
Last modification on : Friday, May 10, 2019 - 5:31:14 PM
Long-term archiving on : Thursday, September 13, 2018 - 11:58:19 AM

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Nicolas P. Rougier. A Density-Driven Method for the Placement of Biological Cells Over Two-Dimensional Manifolds. Frontiers in Neuroinformatics, Frontiers, 2018, 12, ⟨10.3389/fninf.2018.00012⟩. ⟨hal-01617732v2⟩

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