Smart-phones technology and the development of mHealth (Mobile Health) applications offer an opportunity to design intervention tools to influence health behavior changes. The MAVIE-Lab is a mHealth application including a DSS (Desicion Support System) to assist in the personalized evaluation of HLIs (Home, Leisure and Sport Injuries) risk and to promote the adoption of prevention measures. MAVIE-Lab Sports will be the first module of the mobile application. The purpose of this PhD project is to improve a particular module of MAVIE-Lab, devoted to sports (MAVIE-Lab Sports), in different aspects: statistical modeling, design and ergonomics. It also aims to evaluate system usability, acceptability, safety and efficacy. The development structure proposed and executed in this thesis will be replicated for the development of future modules for different types of HLIs. This document develops the argument, objectives and advances in the development of the MAVIE-Lab Sports and the future work.