A review of the evolution of systemic chemotherapy in the management of colorectal cancer, Clinical Colorectal Cancer, vol.14, pp.1-10, 2015. ,
Genetic alterations in colorectal cancer, Gastrointestinal cancer research: GCR, vol.5, pp.19-27, 2012. ,
Expression of E-cadherin and KRAS mutation may serve as biomarkers of cetuximab-based therapy in metastatic colorectal cancer, Oncology Letters, vol.5, pp.1295-1300, 2013. ,
ESMO consensus guidelines for the management of patients with metastatic colorectal cancer, Annals of Oncology: Official Journal of the European Society for Medical Oncology, vol.27, pp.1386-1422, 2016. ,
Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer, Nature Communications, vol.7, p.13665, 2016. ,
Imaging in Colorectal Cancer: Progress and Challenges for the Clinicians, Cancers, vol.8, 2016. ,
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency, New England Journal of Medicine, vol.372, pp.2509-2520, 2015. ,
Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study, The Lancet. Oncology, vol.18, pp.1182-1191, 2017. ,
FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study, The Lancet. Oncology, vol.16, pp.1306-1315, 2015. ,
Clinical Practice Patterns in Chemotherapeutic Treatment Regimens for Metastatic Colorectal Cancer, Clinical Colorectal Cancer, vol.15, pp.135-140, 2016. ,
Role of targeted therapy in metastatic colorectal cancer, World Journal of Gastrointestinal Oncology, vol.8, pp.642-655, 2016. ,
The consensus molecular subtypes of colorectal cancer, Nature Medicine, vol.21, pp.1350-1356, 2015. ,
Cyclin E overexpression impairs progression through mitosis by inhibiting APCCdh1, The Journal of Cell Biology, vol.178, pp.371-385, 2007. ,
Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors, The American Journal of Pathology, vol.170, pp.1793-1805, 2007. ,
Structural basis for the subunit assembly of the anaphase-promoting complex, Nature, vol.470, pp.227-232, 2011. ,
Molecular architecture and mechanism of the anaphase-promoting complex, Nature, vol.513, pp.388-393, 2014. ,
Insights into APC/C: from cellular function to diseases and therapeutics, Cell Division, vol.11, p.9, 2016. ,
A decrease in cyclin B1 levels leads to polyploidization in DNA damage-induced senescence, Cell Biology International, vol.34, pp.645-653, 2010. ,
A single mutation in Securin induces chromosomal instability and enhances cell invasion, European Journal of Cancer, vol.49, pp.500-510, 1990. ,
APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphasepromoting complex, Molecular Biology of the Cell, vol.12, pp.3839-3851, 2001. ,
Ubiquitin chain elongation requires E3-dependent tracking of the emerging conjugate, Molecular Cell, vol.56, pp.232-245, 2014. ,
The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C, Nature, vol.517, pp.631-634, 2015. ,
Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy, Cancer Research, vol.70, pp.4891-4900, 2010. ,
Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships, Breast Cancer Research, vol.7, pp.238-247, 2005. ,
Alterations of anaphase-promoting complex genes in human colon cancer cells, Oncogene, vol.22, pp.1486-1490, 2003. ,
Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters, Oncogene, vol.23, pp.1377-1391, 2004. ,
URL : https://hal.archives-ouvertes.fr/hal-01612151
DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy, Journal of the National Cancer Institute, vol.103, pp.863-875, 2011. ,
APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability, Cancer Discovery, vol.7, pp.218-233, 2017. ,
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity, Nature, vol.483, pp.603-607, 2012. ,
, The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer, Nature, vol.487, pp.330-337, 2012.
Epigenetic and genetic alterations in Netrin-1 receptors UNC5c and DCC in human colon cancer, Gastroenterology, vol.133, pp.1849-1857, 2007. ,
Genomic instability and colon carcinogenesis: from the perspective of genes, Frontiers in Oncology, vol.3, p.130, 2013. ,
Chromosomal instability confers intrinsic multidrug resistance, Cancer Research, vol.71, pp.1858-1870, 2011. ,
Loss of Bcl-2 expression in colon cancer: a prognostic factor for recurrence in stage II colon cancer, Surgical Oncology, vol.18, pp.357-365, 2009. ,
Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/betacatenin complex, Oncology Reports, vol.21, pp.57-63, 2009. ,
New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress, Nucleic Acids Research, vol.44, pp.4745-4762, 2016. ,
CDC20 maintains tumor initiating cells, Oncotarget, vol.6, pp.13241-13254, 2015. ,
Knockdown expression of Apc11 leads to cell-cycle distribution reduction in G2/M phase, Genetics and molecular research: GMR, vol.11, pp.2814-2822, 2012. ,
Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation, Genes & Development, vol.18, pp.88-98, 2004. ,
The anaphase-promoting complex (APC): the sum of its parts?, Biochemical Society Transactions, vol.32, pp.724-727, 2004. ,
, SCientifiC RepoRts |, vol.8, 2018.
The anaphase-promoting complex is required in both dividing and quiescent cells during zebrafish development, Developmental Biology, vol.303, pp.144-156, 2007. ,
Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21cip1/Waf1, Cell Death & Disease, vol.7, p.2074, 2016. ,
Discovery and saturation analysis of cancer genes across 21 tumour types, Nature, vol.505, pp.495-501, 2014. ,
The anaphase-promoting complex/cyclosome is an E3 ubiquitin ligase for Mdm2, Cell Cycle, vol.13, pp.2101-2109, 2014. ,
DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling, Nucleic Acids Research, vol.37, pp.2688-2698, 2009. ,
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs, The EMBO journal, vol.33, pp.2643-2658, 2014. ,
The anaphase-promoting complex: proteolysis in mitosis and beyond, Molecular Cell, vol.9, pp.931-943, 2002. ,
The anaphase promoting complex/cyclosome: a machine designed to destroy, Nature Reviews. Molecular Cell Biology, vol.7, pp.644-656, 2006. ,
Regulation of APC/C activators in mitosis and meiosis, Annual Review of Cell and Developmental Biology, vol.24, pp.475-499, 2008. ,
Cubism and the cell cycle: the many faces of the APC/C, Nature Reviews. Molecular Cell Biology, vol.12, pp.427-438, 2011. ,
Transcription-independent function of Polycomb group protein PSC in cell cycle control, Science, vol.336, pp.744-747, 2012. ,
Targeting mitotic exit with hyperthermia or APC/C inhibition to increase paclitaxel efficacy, Cell Cycle, vol.12, pp.2598-2607, 2013. ,
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C, Nature, vol.514, pp.646-649, 2014. ,
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines, Oncogene, vol.20, pp.5025-5032, 2001. ,
Differential display cloning identifies motility-related protein (MRP1/CD9) as highly expressed in primary compared to metastatic human colon carcinoma cells, Cancer Research, vol.57, pp.2593-2597, 1997. ,
Contribution of cell culture, RNA extraction, and reverse transcription to the measurement error in quantitative reverse transcription polymerase chain reaction-based gene expression quantification, Analytical Biochemistry, vol.393, pp.29-35, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00539350
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype, British Journal of Cancer, vol.101, pp.673-683, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00539351
Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer, Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, vol.28, pp.3219-3226, 2010. ,
MSH2 and MLH1 immunodetection and the prognosis of colon cancer, International Journal of Oncology, vol.19, pp.891-895, 2001. ,
Distinct and Complementary Information Provided by Use of Tissue and DNA Microarrays in the Study of Breast Tumor Markers, The American Journal of Pathology, vol.161, pp.1223-1233, 2002. ,
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data, Cancer Discovery, vol.2, pp.401-404, 2012. ,
, , 2017.
Handling Missing Values with Regularized Iterative Multiple Correspondence Analysis, Journal of Classification, vol.29, pp.91-116, 2012. ,
DOI : 10.1007/s00357-012-9097-0
URL : https://hal.archives-ouvertes.fr/hal-00647378
, Multiple Imputation for Nonresponse in Surveys. Wiley Series in Probability and Statistics, 1987.
Evaluating cell lines as tumour models by comparison of genomic profiles, Nature Communications, vol.4, p.2126, 2013. ,