Anticipation via canards in excitable systems

Abstract : Neurons can anticipate incoming signals by exploiting a physiological mechanism not well understood. This article offers a novel explanation on how a receiver neuron can predict the sender's dynamics in a unidirectionally-coupled configuration, in which both sender-receiver follow the evolution of a multi-scale excitable system. We present a novel theoretical view point based on a mathematical object, called canard, to explain anticipation in excitable systems. We provide a numerical approach, which allows to determine the transient effects of canards. To demonstrate the general validity of canard-mediated anticipation in the context of excitable systems, we illustrate our framework in two examples, a multi-scale radio-wave circuit (the van der Pol model) that inspired a caricature neuronal model (the FitzHugh-Nagumo model) and a biophysical neuronal model (a 2-dimentional reduction of the Hodgkin-Huxley model), where canards act as messengers to the senders' prediction. We also propose an experimental paradigm that would enable experimental neuroscientists to validate our predictions. We conclude with an outlook to possible fascinating research avenues to further unfold the mechanisms underpinning anticipation. We envisage that our approach can be employed to a wider class of excitable systems with appropriate theoretical extensions. Anticipation appears as a counter-intuitive observation in a wide range of dynamical systems ranging from biology to engineering applications. It can occur in unidirectionally coupled systems when the receiver is subject to a self-delayed feedback in addition to a signal coming from the sender. This particular interaction permits the receiver to predict the future trajectory of the sender. Anticipation can occur transiently, thus straightforwardly denoted anticipation, or in long-term dynamics, in which case it is referred to as anticipated synchronization. In this study, we focus on both aspects of anticipatory dynamics in the context of excitable systems and explain it via a counter-intuitive phenomenon, namely canards. Canard trajectories structure the excitability and synchronization properties of multiple timescale systems exhibiting excitable dynamics. By developing a theoretical framework enhanced by numerical continuation, we show that the underlying canard structure in excitable systems is responsible for delaying sub-threshold solutions, but anticipating the spiking ones. We also propose an experimental set up that would enable experimentalists to observe anticipated behavior in neural systems, in particular in type-II neu-rons.
Type de document :
Article dans une revue
Chaos: An Interdisciplinary Journal of Nonlinear Science, AIP, In press
Liste complète des métadonnées

https://hal.inria.fr/hal-01960691
Contributeur : Elif Koksal Ersoz <>
Soumis le : mercredi 19 décembre 2018 - 15:12:16
Dernière modification le : jeudi 20 décembre 2018 - 01:28:07

Fichier

kdmr_chaos_rev2.pdf
Fichiers produits par l'(les) auteur(s)

Identifiants

  • HAL Id : hal-01960691, version 1

Collections

Citation

Elif Köksal Ersöz, Mathieu Desroches, Claudio Mirasso, Serafim Rodrigues. Anticipation via canards in excitable systems. Chaos: An Interdisciplinary Journal of Nonlinear Science, AIP, In press. 〈hal-01960691〉

Partager

Métriques

Consultations de la notice

38

Téléchargements de fichiers

56