Pattern Structures for Identifying Biclusters with Coherent Sign Changes

Nyoman Juniarta; Victor Codocedo; Miguel Couceiro; Mehdi Kaytoue; Amedeo Napoli

Pattern Structures for Identifying Biclusters with Coherent Sign Changes

Nyoman Juniarta ¹ Victor Codocedo ² Miguel Couceiro ¹ Mehdi Kaytoue ² Amedeo Napoli ¹

1 ORPAILLEUR - Knowledge representation, reasonning

Inria Nancy - Grand Est, LORIA - NLPKD - Department of Natural Language Processing & Knowledge Discovery

2 DM2L - Data Mining and Machine Learning

LIRIS - Laboratoire d'InfoRmatique en Image et Systèmes d'information

Abstract : In this paper we are studying the task of nding coherent-sign-changes biclusters in a binary matrix. This task can be applied to the interpretation of gene expression data, where such a bicluster represents a set of experiments that aect a set of genes in a consistent way. We start with a binary table and study biclustering methods based on FCA and partition pattern structures. Pattern concepts provide biclusters and their hierarchical relation, which can be used to analyze the prole of genes in the given expression data. Our approach is purely symbolic, so we can detect larger biclusters and work with rather complex data.

Keywords : biclustering FCA gene expression pattern structures

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Computer Science [cs]

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https://hal.inria.fr/hal-02166713
Contributor : Nyoman Juniarta <>
Submitted on : Thursday, June 27, 2019 - 10:12:31 AM
Last modification on : Wednesday, July 10, 2019 - 1:01:50 AM

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