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Intensity Harmonization Techniques Influence Radiomics Features and Radiomics-based Predictions in Sarcoma Patients

Abstract : Intensity harmonization techniques (IHT) are mandatory to homogenize multicentric MRIs before any quantitative analysis because signal intensities (SI) do not have standardized units. Radiomics combine quantification of tumors' radiological phenotype with machine-learning to improve predictive models, such as metastasticrelapse-free survival (MFS) for sarcoma patients. We post-processed the initial T2weighted-imaging of 70 sarcoma patients by using 5 IHTs and extracting 45 radiomics features (RFs), namely: classical standardization (IHTstd), standardization per adipose tissue SIs (IHTfat), histogram-matching with a patient histogram
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https://hal.inria.fr/hal-03050686
Contributor : Olivier Saut <>
Submitted on : Thursday, December 10, 2020 - 10:28:52 AM
Last modification on : Friday, December 11, 2020 - 3:46:39 AM

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Amandine Crombé, Michèle Kind, David Fadli, François Le Loarer, Antoine Italiano, et al.. Intensity Harmonization Techniques Influence Radiomics Features and Radiomics-based Predictions in Sarcoma Patients. Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-72535-0⟩. ⟨hal-03050686⟩

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