Simulation of Astrocytic Calcium Dynamics in Lattice Light Sheet Microscopy Images - Archive ouverte HAL Access content directly
Conference Papers Year :

Simulation of Astrocytic Calcium Dynamics in Lattice Light Sheet Microscopy Images

(1, 2) , (3) , (4) , (5) , (6, 7) , (3) , (1, 2)
1
2
3
4
5
6
7

Abstract

Astrocytes regulate neuronal information processing through a variety of spatio-temporal calcium signals. Recent advances in calcium imaging have started to shine light on astrocytic activity, but the complexity and size of the recorded data strongly call for more advanced computational analysis tools. Their development is currently hindered by the lack of reliable, labeled annotations that are essential for the evaluation of algorithms and the training of learning-based methods. To solve this labeling problem, we have designed a generator of 2D/3D lattice light sheet microscopy (LLSM) sequences which realistically depict the calcium dynamics of astrocytes. By closely modeling calcium kinetics in real astrocytic ramifications, the generated datasets open the door for the deployment of convolutional neural networks in LLSM.
Fichier principal
Vignette du fichier
Badoual_ISBI.pdf (3.52 Mo) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-03106797 , version 1 (12-01-2021)

Identifiers

Cite

Anaïs Badoual, Misa Arizono, Audrey Denizot, Mathieu Ducros, Hugues Berry, et al.. Simulation of Astrocytic Calcium Dynamics in Lattice Light Sheet Microscopy Images. ISBI 2021 - IEEE International Symposium on Biomedical Imaging, Apr 2021, Nice, France. pp.1-5, ⟨10.1109/ISBI48211.2021.9433984⟩. ⟨hal-03106797⟩
236 View
289 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More