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YASS: enhancing the sensitivity of DNA similarity search

Laurent Noé 1 Gregory Kucherov 1
1 ADAGE - Applying discrete algorithms to genomics
INRIA Lorraine, LORIA - Laboratoire Lorrain de Recherche en Informatique et ses Applications
Abstract : YASS is a DNA local alignment tool based on an efficient and sensitive filtering algorithm. It applies transition-constrained seeds to specify the most probable conserved motifs between homologous sequences, combined with a flexible hit criterion used to identify groups of seeds that are likely to exhibit significant alignments. A web interface ( is available to upload input sequences in fasta format, query the program and visualize the results obtained in several forms (dot-plot, tabular output and others). A standalone version is available for download from the web page.
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Contributor : Gregory Kucherov <>
Submitted on : Tuesday, November 15, 2005 - 12:42:13 PM
Last modification on : Wednesday, December 9, 2020 - 6:02:06 PM

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Laurent Noé, Gregory Kucherov. YASS: enhancing the sensitivity of DNA similarity search. Nucleic Acids Research, Oxford University Press, 2005, 33 (Web server issue), pp.W540--W543. ⟨10.1093/nar/gki478⟩. ⟨inria-00000721⟩



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