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Multiscale modeling of alternative splicing regulation

Damien Eveillard 1 Delphine Ropers 2 Hidde de Jong 3 Christiane Branlant 2 Alexander Bockmayr 1
1 MODBIO - Computational models in molecular biology
INRIA Lorraine, LORIA - Laboratoire Lorrain de Recherche en Informatique et ses Applications
2 MAEM - Maturation des ARN et enzymologie moléculaire
3 HELIX - Computer science and genomics
Inria Grenoble - Rhône-Alpes, LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558
Abstract : Alternative splicing is a key process in post-transcriptional regulation, by which several kinds of mature RNA can be obtained from the same premessenger RNA. Using a constraint programming approach, we model the alternative splicing regulation at different scales (single site vs.\ multiple sites), thus exploiting different types of available experimental data.
Mots-clés : bioinformatique alternative splicing bioinformatics constraint programming programmation par contraintes épissage alternatif
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Conference papers
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https://hal.inria.fr/inria-00099792
Contributor : Publications Loria <>
Submitted on : Tuesday, September 26, 2006 - 9:41:15 AM
Last modification on : Monday, February 17, 2020 - 3:50:19 PM

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  • HAL Id : inria-00099792, version 1

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INRIA | CNRS | BIOENVIS | UNIV-NANTES | LINA-COMBI | LINA | LORIA | CGE | UNIV-LORRAINE | UNIV-LYON1 | UDL

Citation

Damien Eveillard, Delphine Ropers, Hidde de Jong, Christiane Branlant, Alexander Bockmayr. Multiscale modeling of alternative splicing regulation. International Workshop on Computational Methods in Systems Biology - CMSB'03, 2003, Rovereto, Italie, pp.75-87. ⟨inria-00099792⟩

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