The White Matter Integrity Disruption in Schizophrenia

Abstract : Diffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that analyzed by using a rigorous voxel-based approach. We found that fractional anisotropy in white matter of the patients was lower than that in controls at the cerebral peduncle, frontal regions, inferior temporal gyrus, medial parietal lobes, hippocampal gyrus, insula, right anterior cingulun bundle and right corona radiata. These results suggested that white matter integrity of the whole brain was disrupted in early illness onset of schizophrenia.
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Article dans une revue
NeuroReport, Lippincott, Williams & Wilkins, 2006, NeuroReport, 17 (1), pp.23-26
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https://hal.inria.fr/inria-00123768
Contributeur : Chine Publications Liama <>
Soumis le : jeudi 11 janvier 2007 - 09:27:07
Dernière modification le : mardi 24 avril 2018 - 13:55:14

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  • HAL Id : inria-00123768, version 1

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Yihui Hao, Zhening Liu, Tianzi Jiang, Gaolang Gong, Haihong Liu, et al.. The White Matter Integrity Disruption in Schizophrenia. NeuroReport, Lippincott, Williams & Wilkins, 2006, NeuroReport, 17 (1), pp.23-26. 〈inria-00123768〉

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