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Comparative analysis of RNA genes: the caRNAc software


RNA genes are ubiquitous in the cell and are involved in a number of biochemical processes. Since there is a close relationship between function and structure, software tools that predict the secondary structure of non-coding RNAs from the base sequence are very helpful. In this article, we focus our attention on the inference of conserved secondary structure for a group of homologous RNA sequences. We present the caRNAc software which enables the analysis of families of homologous sequences without prior alignment. The method relies both on comparative analysis and thermodynamic information.
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inria-00178557 , version 1 (12-10-2007)


  • HAL Id : inria-00178557 , version 1


Helene Touzet. Comparative analysis of RNA genes: the caRNAc software. Nicholas Bergman. Comparative Genomics, Volume 1, Humana Press, 2007, Methods in Molecular Biology, 978-1-58829-693-1. ⟨inria-00178557⟩
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