Abstract : Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants. In this paper an evolutionary approach is proposed to discover new proteins or protein variants thanks a "de novo sequencing" method. This approach has been experimented on a specific grid called Grid5000 with simulated spectra and also real spectra.
https://hal.inria.fr/inria-00270867 Contributor : Jean-Charles BoissonConnect in order to contact the contributor Submitted on : Tuesday, April 8, 2008 - 9:38:13 AM Last modification on : Thursday, January 20, 2022 - 5:27:52 PM Long-term archiving on: : Friday, May 21, 2010 - 1:26:02 AM
Jean-Charles Boisson, Laetitia Jourdan, El-Ghazali Talbi, Christian Rolando. A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids. AINA 2006, HIPCOMB Workshop, Apr 2006, Vienne, Austria. ⟨inria-00270867⟩