Skip to Main content Skip to Navigation
Conference papers

Comparing Voronoi and Laguerre tessellations in the protein-protein docking context

Abstract : Most proteins fulfill their functions through the interaction with other proteins. Because most of these interactions are transitory, they are difficult to detect experimentally, and obtaining the structure of the complex is generally not possible. Consequently, prediction of the existence of these interactions and of the structure of the resulting complex has received a lot of attention in the last decade. However, proteins are very complex objects, and classical computing methods have lead to computer-time consuming methods, whose accuracy is not sufficient for largescale exploration of the so-called “interactome”, the ensemble of protein-protein complexes in the cell. In order to design an accurate and high-throughput prediction method for protein-protein docking, the first step was to model a protein structure using a formalism allowing fast computation, without losing the intrinsic properties of the object. In our work, we have tested two different, but related, formalisms: the Voronoi and Laguerre tessellations. We present here a comparison of these two models in the context of protein-protein docking.
Complete list of metadata

Cited literature [20 references]  Display  Hide  Download
Contributor : Julie Bernauer Connect in order to contact the contributor
Submitted on : Tuesday, November 3, 2009 - 4:46:09 PM
Last modification on : Thursday, August 5, 2021 - 3:47:53 AM
Long-term archiving on: : Thursday, June 17, 2010 - 7:14:39 PM


Files produced by the author(s)


  • HAL Id : inria-00429618, version 1



Thomas Bourquard, Julie Bernauer, Jérôme Azé, Anne Poupon. Comparing Voronoi and Laguerre tessellations in the protein-protein docking context. Sixth annual International Symposium on Voronoi Diagrams, F. Anton and J. Andreas Bærentzen - Technical University of Denmark, Jun 2009, Copenhagen, Denmark. ⟨inria-00429618⟩



Record views


Files downloads