A poroelastic model valid in large strains with applications to perfusion in cardiac modeling

Dominique Chapelle 1 Jacques Sainte-Marie 1 Jean-Frédéric Gerbeau 2 Irene Vignon-Clementel 2
2 REO - Numerical simulation of biological flows
LJLL - Laboratoire Jacques-Louis Lions, Inria Paris-Rocquencourt, UPMC - Université Pierre et Marie Curie - Paris 6
Abstract : This paper is motivated by the modeling of blood flows through the beating myocardium, namely cardiac perfusion. As in other works, perfusion is modeled here as a flow through a poroelastic medium. The main contribution of this study is the derivation of a general poroelastic model valid for a nearly incompressible medium which experiences finite deformations. A numerical procedure is proposed to iteratively solve the porous flow and the nonlinear poroviscoelastic problems. Three-dimensional numerical experiments are presented to illustrate the model. The first test cases consist of typical poroelastic configurations: swelling and complete drainage. Finally, a simulation of cardiac perfusion is presented in an idealized left ventricle embedded with active fibers. Results show the complex temporal and spatial interactions of the muscle and blood, reproducing several key phenomena observed in cardiac perfusion.
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Dominique Chapelle, Jacques Sainte-Marie, Jean-Frédéric Gerbeau, Irene Vignon-Clementel. A poroelastic model valid in large strains with applications to perfusion in cardiac modeling. Computational Mechanics, Springer Verlag, 2010, 46 (1), pp.91-101. ⟨10.1007/s00466-009-0452-x⟩. ⟨inria-00542672⟩

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