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Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.

Abstract : Our multiple CART strategy proved to be an effective tool to identify new Wnt/beta-catenin pathway targets based on the study of their regulatory regions in the human genome. In particular, several of these genes represent a new group of transcriptional dependent targets of the canonical Wnt pathway. The functions of these genes indicate that they are involved in pathophysiology related to Alzheimer's disease or other brain disorders.
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https://hal.inria.fr/inria-00547316
Contributor : David James Sherman <>
Submitted on : Thursday, December 16, 2010 - 5:19:09 AM
Last modification on : Thursday, February 11, 2021 - 2:54:03 PM

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Christian Hödar, Rodrigo Assar, Marcela Colombres, Andrés Aravena, Leonardo Pavez, et al.. Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.. BMC Genomics, BioMed Central, 2010, 11, pp.348. ⟨10.1186/1471-2164-11-348⟩. ⟨inria-00547316⟩

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