Inferring sparse Gaussian graphical models with latent structure

Christophe Ambroise 1 Julien Chiquet 1 Catherine Matias 1
1 SG - Laboratoire Statistique et Génome
Abstract : Our concern is selecting the concentration matrix's nonzero coefficients for a sparse Gaussian graphical model in a high-dimensional setting. This corresponds to estimating the graph of conditional dependencies between the variables. We describe a novel framework taking into account a latent structure on the concentration matrix. This latent structure is used to drive a penalty matrix and thus to recover a graphical model with a constrained topology. Our method uses an $\ell_1$ penalized likelihood criterion. Inference of the graph of conditional dependencies between the variates and of the hidden variables is performed simultaneously in an iterative \textsc{em}-like algorithm. The performances of our method is illustrated on synthetic as well as real data, the latter concerning breast cancer.
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Electronic journal of statistics , Shaker Heights, OH : Institute of Mathematical Statistics, 2009, 〈10.1214/08-EJS314〉
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https://hal.inria.fr/inria-00591491
Contributeur : Julien Chiquet <>
Soumis le : lundi 9 mai 2011 - 14:24:50
Dernière modification le : jeudi 11 janvier 2018 - 06:12:20

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Christophe Ambroise, Julien Chiquet, Catherine Matias. Inferring sparse Gaussian graphical models with latent structure. Electronic journal of statistics , Shaker Heights, OH : Institute of Mathematical Statistics, 2009, 〈10.1214/08-EJS314〉. 〈inria-00591491〉

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